ECMDB: Serine/threonine transporter sstT (P0AGE5)

Identification

Name:

Serine/threonine transporter sstT

Synonyms:

Na(+)/serine-threonine symporter

Gene Name:

sstT

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in sodium:dicarboxylate symporter activity

Specific Function:

Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

Cellular Location:

Cell inner membrane; Multi-pass membrane protein

SMPDB Pathways:

Biosynthesis of siderophore group nonribosomal peptides PW000760
GLYCINE BIOSYNTHESIS PW000808
inner membrane transport PW000786

KEGG Pathways:

Biosynthesis of siderophore group nonribosomal peptides ec01053

Transports:

Transport References:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Component
cell part
membrane
Function
carboxylic acid transmembrane transporter activity
dicarboxylic acid transmembrane transporter activity
organic acid transmembrane transporter activity
sodium:dicarboxylate symporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
carboxylic acid transport
dicarboxylic acid transport
establishment of localization
organic acid transport
transport

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>1245 bp
ATGCGTTTATCTCTCCCTCGCCTGAAAATGCCGCGCCTGCCAGGATTCAGTATCCTGGTC
TGGATCTCCACGGCGCTAAAGGGCTGGGTGATGGGCTCGCGGGAAAAAGATACCGACAGC
CTGATCATGTACGATCGCACCTTACTGTGGCTGACCTTCGGCCTCGCGGCGATTGGCTTT
ATCATGGTGACCTCGGCGTCAATGCCCATAGGGCAACGCTTAACCAACGATCCGTTCTTC
TTCGCGAAGCGTGATGGTGTCTATCTGATTTTGGCGTTTATTCTGGCGATCATTACGCTG
CGTCTGCCGATGGAGTTCTGGCAACGCTACAGTGCCACGATGCTGCTCGGATCTATCATC
CTGCTGATGATCGTGCTGGTAGTGGGGAGCTCGGTTAAAGGGGCATCGCGTTGGATCGAT
CTCGGTTTGCTGCGTATCCAGCCTGCTGAGCTGACAAAACTGTCGCTGTTTTGCTATATC
GCCAACTATCTGGTGCGTAAAGGTGACGAAGTACGTAATAACCTGCGCGGCTTCCTGAAA
CCGATGGGCGTGATTCTGGTGTTGGCAGTGTTACTGCTGGCACAGCCAGACCTTGGTACG
GTGGTGGTGTTGTTTGTGACTACGCTGGCGATGTTGTTCCTGGCGGGAGCGAAATTGTGG
CAGTTCATTGCCATTATCGGTATGGGCATTTCAGCGGTTGTGTTGCTGATACTCGCCGAA
CCGTACCGTATCCGCCGTGTTACCGCATTCTGGAACCCGTGGGAAGATCCCTTTGGCAGC
GGCTATCAGTTAACGCAATCGCTGATGGCGTTTGGTCGCGGCGAACTGTGGGGACAAGGT
TTAGGTAACTCTGTACAAAAACTGGAGTATCTGCCGGAAGCGCACACTGACTTTATTTTC
GCCATTATCGGCGAAGAACTGGGGTATGTCGGTGTGGTGCTGGCACTTTTAATGGTATTC
TTCGTCGCTTTTCGCGCGATGTCGATTGGCCGTAAAGCATTAGAAATTGACCACCGTTTT
TCCGGTTTTCTCGCCTGTTCTATTGGCATCTGGTTTAGCTTCCAGGCGCTGGTTAACGTA
GGCGCGGCGGCGGGGATGTTACCGACCAAAGGTCTGACATTGCCGCTGATCAGTTACGGT
GGTTCGAGCTTACTGATTATGTCGACAGCCATCATGATGCTGTTGCGTATTGATTATGAA
ACGCGTCTGGAGAAAGCGCAGGCGTTTGTACGAGGTTCACGATGA

Protein Properties

Pfam Domain Function:

SDF (PF00375 )

Protein Residues:

414

Protein Molecular Weight:

43477

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

16-36
46-66
84-104
143-163
180-200
218-238
300-320
332-352

Protein Sequence:

>Serine/threonine transporter sstT
MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPI
LVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDIS
PPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLGFALRHGNETTKNLVNDMSNA
VTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWW
KIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINM
AGAAITITVLTLAAVNTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFG
ISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDDRLANSALRN

References

External Links:

Resource	Link
Uniprot ID:	P0AGE5
Uniprot Name:	SSTT_ECO57
GenBank Gene ID:	AE005174
Genebank Protein ID:	12512792
EchoBASE ID:	EB2590
CCDB:	SSTT_ECO57

General Reference:

Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551