Probable oxalyl-CoA decarboxylase (P0AFI0)

Identification
Name:Probable oxalyl-CoA decarboxylase
Synonyms:Not Available
Gene Name:oxc
Enzyme Class:
Biological Properties
General Function:Involved in oxalyl-CoA decarboxylase activity
Specific Function:Oxalyl-CoA = formyl-CoA + CO(2)
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Hydrogen ion + 1.0Oxalyl-CoA ↔ 1.0Carbon dioxide + 1.0Formyl-CoA
ReactionCard
1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Oxalyl-CoA ↔ 1.0Formyl-CoA + 1.0Carbon dioxide
ReactionCard
1.0Thumb+1.0Thumb ? 1.0Thumb+1.0Thumb
1.0Hydrogen ion + 1.0Oxalyl-CoA ? 1.0Carbon dioxide + 1.0Formyl-CoA
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Hydrogen ion + 1.0Oxalyl-CoA ↔ 1.0Carbon dioxide + 1.0Formyl-CoA
ReactionCard
1.0Thumb+1.0Thumb ? 1.0Thumb+1.0Thumb
1.0Hydrogen ion + 1.0Oxalyl-CoA ? 1.0Carbon dioxide + 1.0Formyl-CoA
ReactionCard
Complex Reactions:
1.0Thumb → 1.0Thumb+1.0Thumb
1.0Oxalyl-CoA → 1.0Formyl-CoA + 1.0Carbon dioxide
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB04030Carbon dioxideMetaboCard
ECMDB03419Formyl-CoAMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB20182Oxalyl-CoAMetaboCard
GO Classification:
Function
binding
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
cation binding
ion binding
lyase activity
magnesium ion binding
metal ion binding
oxalyl-CoA decarboxylase activity
thiamin pyrophosphate binding
vitamin binding
Process
carboxylic acid metabolic process
cellular metabolic process
dicarboxylic acid metabolic process
metabolic process
organic acid metabolic process
oxalate catabolic process
oxalate metabolic process
oxoacid metabolic process
Gene Properties
Blattner:b2373
Gene OrientationCounterclockwise
Centisome Percentage:53.63
Left Sequence End2488278
Right Sequence End2489972
Gene Sequence:
>1695 bp
ATGTCAGATCAACTTCAAATGACAGATGGTATGCATATCATCGTTGAAGCATTAAAACAG
AATAATATTGACACTATTTATGGTGTTGTAGGTATTCCTGTGACGGATATGGCACGCCAT
GCCCAGGCGGAAGGCATTCGTTATATTGGTTTTCGTCATGAGCAGTCGGCAGGCTATGCC
GCTGCGGCAAGCGGTTTTCTTACCCAAAAACCGGGGATCTGCCTGACAGTTTCTGCGCCA
GGATTCCTCAATGGTTTGACCGCATTGGCCAACGCAACGGTAAATGGTTTTCCGATGATC
ATGATTAGCGGCTCCAGCGACCGCGCGATCGTCGACCTACAGCAAGGTGATTATGAAGAG
CTGGACCAAATGAATGCGGCAAAACCGTATGCCAAAGCAGCATTTCGCGTTAATCAGCCG
CAGGATCTTGGCATTGCATTGGCACGCGCTATCCGGGTCTCTGTATCGGGTCGCCCTGGC
GGAGTTTATCTTGATTTGCCAGCAAATGTCCTGGCCGCGACGATGGAAAAAGACGAAGCG
TTAACCACGATTGTTAAAGTTGAAAATCCGTCGCCAGCATTATTGCCATGCCCGAAGTCA
GTCACTAGCGCAATTTCGCTTTTAGCAAAAGCTGAACGGCCATTAATTATCCTTGGCAAA
GGCGCGGCGTATTCACAAGCTGATGAACAGCTTCGTGAATTTATTGAAAGTGCTCAGATT
CCATTCCTGCCAATGTCTATGGCGAAAGGGATCCTTGAAGATACGCATCCACTTTCTGCG
GCAGCTGCGCGTTCGTTTGCCCTGGCAAATGCTGACGTTGTCATGCTTGTTGGTGCACGA
CTGAATTGGTTATTGGCACACGGTAAAAAAGGATGGGCGGCAGATACACAGTTTATTCAA
CTGGATATTGAACCGCAGGAAATTGACAGCAACCGCCCCATTGCTGTGCCAGTCGTTGGT
GATATTGCATCCAGTATGCAAGGTATGCTGGCAGAACTGAAACAAAACACATTTACGACT
CCACTGGTATGGCGCGATATTTTAAATATCCACAAGCAGCAAAATGCACAAAAAATGCAT
GAAAAATTAAGTACAGATACTCAACCATTAAATTACTTTAATGCATTAAGTGCTGTGCGC
GACGTATTGCGCGAGAACCAGGATATTTATTTAGTTAATGAAGGTGCAAATACCCTGGAT
AATGCACGAAATATTATTGATATGTATAAACCACGTCGTCGTCTGGATTGTGGTACCTGG
GGTGTCATGGGCATCGGTATGGGCTATGCCATCGGTGCTAGCGTGACTTCTGGTTCTCCG
GTTGTCGCCATTGAAGGTGATAGTGCTTTTGGTTTCAGTGGGATGGAAATTGAAACGATT
TGTCGATATAACCTGCCGGTGACGATCGTTATTTTTAATAATGGCGGCATCTACAGAGGA
GACGGTGTTGATCTCAGTGGCGCTGGTGCACCATCACCAACGGATCTGTTGCACCATGCA
AGGTATGACAAATTAATGGATGCGTTTCGTGGCGTTGGCTATAACGTCACCACGACAGAT
GAACTTCGTCATGCTTTAACCACCGGTATTCAGTCGCGCAAACCGACCATTATTAATGTG
GTCATCGACCCTGCAGCAGGAACTGAAAGTGGCCATATTACCAAACTTAACCCAAAACAA
GTCGCTGGTAATTAA
Protein Properties
Pfam Domain Function:
Protein Residues:564
Protein Molecular Weight:60581
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Probable oxalyl-CoA decarboxylase
MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIGFRHEQSAGYA
AAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEE
LDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEKDEA
LTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQI
PFLPMSMAKGILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQ
LDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQNTFTTPLVWRDILNIHKQQNAQKMH
EKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLDNARNIIDMYKPRRRLDCGTW
GVMGIGMGYAIGASVTSGSPVVAIEGDSAFGFSGMEIETICRYNLPVTIVIFNNGGIYRG
DGVDLSGAGAPSPTDLLHHARYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINV
VIDPAAGTESGHITKLNPKQVAGN
References
External Links:
ResourceLink
Uniprot ID:P0AFI0
Uniprot Name:OXC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85675382
Ecogene ID:EG14143
Ecocyc:EG14143
ColiBase:b2373
Kegg Gene:b2373
EchoBASE ID:EB3895
CCDB:OXC_ECOLI
BacMap:16130305
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837