Identification
Name:Virulence factor mviN homolog
Synonyms:Not Available
Gene Name:mviN
Enzyme Class:Not Available
Biological Properties
General Function:Involved in lipid transporter activity
Specific Function:Specific function unknown
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:
KEGG Pathways:
Transports:
Transport References:Not Available
Complex Reactions:
1.0Thumb+1.0two linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)1.0Thumb+1.0Thumb+1.0three linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)
1.0Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + 1.0two linked disacharide pentapeptide murein units (uncrosslinked, middle of chain) → 1.0Hydrogen ion + 1.0Undecaprenyl diphosphate + 1.0three linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)
ReactionCard
2.0Thumb2.0Thumb+2.0Thumb+1.0two linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)
Metabolites:
ECMDB IDNameView
ECMDB21225Hydrogen ionMetaboCard
ECMDB20290N-Acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamineMetaboCard
ECMDB01469Undecaprenyl diphosphateMetaboCard
ECMDB20212Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b1069
Gene OrientationClockwise
Centisome Percentage:24.29
Left Sequence End1127062
Right Sequence End1128597
Gene Sequence:
>1536 bp
ATGATGAAAATGCGTTGGTTGAGTGCTGCAGTAATGTTAACCCTGTATACATCTTCAAGC
TGGGCTTTCAGTATTGATGATGTCGCAAAGCAAGCTCAATCTTTAGCCGGGAAAGGCTAC
GAGACGCCCAAAAGCAACTTGCCCTCCGTTTTCCGCGATATGAAATACGCGGACTATCAG
CAGATCCAGTTTAATCATGACAAAGCGTACTGGAACAATCTGAAGACCCCATTCAAACTC
GAGTTCTACCATCAGGGTATGTACTTCGATACCCCGGTCAAAATAAATGAAGTGACTGCC
ACCGCAGTCAAACGAATCAAATACAGCCCGGATTATTTCACTTTCGGCGATGTTCAGCAT
GACAAAGATACGGTAAAAGACCTTGGCTTTGCCGGTTTTAAAGTGCTTTACCCGATCAAC
AGCAAAGATAAAAACGATGAAATCGTCAGCATGCTCGGGGCCAGCTATTTCCGCGTGATT
GGTGCAGGTCAGGTTTATGGCCTTTCTGCCCGCGGCCTGGCAATTGATACCGCCTTGCCA
TCGGGTGAAGAATTTCCGCGCTTCAAAGAGTTCTGGATCGAGCGTCCAAAACCGACTGAT
AAACGTTTAACCATCTATGCATTGCTTGACTCGCCGCGTGCGACAGGTGCTTACAAATTC
GTGGTTATGCCAGGGCGTGACACGGTTGTGGATGTGCAGTCGAAAATCTATCTGCGCGAT
AAAGTCGGCAAACTGGGGGTTGCACCGTTAACCAGTATGTTCCTGTTTGGGCCGAACCAA
CCGTCGCCTGCAAATAACTATCGTCCGGAGTTGCACGACTCTAACGGTCTCTCTATCCAT
GCCGGTAATGGCGAATGGATCTGGCGTCCGTTGAATAACCCGAAACATTTAGCGGTCAGC
AGCTTCTCCATGGAAAACCCGCAAGGCTTTGGTCTGTTGCAGCGCGGTCGTGATTTCTCC
CGCTTTGAAGATCTCGATGATCGTTACGATCTCCGTCCAAGCGCATGGGTGACTCCGAAA
GGGGAGTGGGGTAAAGGCAGCGTTGAGCTGGTGGAAATTCCAACCAACGATGAAACCAAC
GATAACATCGTCGCTTACTGGACGCCGGATCAGCTGCCGGAGCCGGGTAAAGAGATGAAC
TTTAAATACACCATCACCTTCAGCCGTGATGAAGACAAACTGCATGCGCCAGATAACGCA
TGGGTGCAACAAACGCGTCGTTCAACGGGGGATGTGAAGCAGTCGAACCTGATTCGCCAG
CCTGACGGTACTATCGCCTTTGTGGTCGATTTTACCGGCGCAGAGATGAAAAAACTGCCA
GAGGATACCCCGGTCACAGCGCAAACCAGCATTGGTGATAATGGTGAGATAGTTGAAAGC
ACGGTGCGCTATAACCCGGTTACCAAAGGCTGGCGTCTGGTGATGCGTGTGAAAGTGAAA
GATGCCAAGAAAACCACTGAAATGCGTGCTGCGCTGGTGAATGCCGATCAGACGTTGAGT
GAAACCTGGAGCTACCAGTTACCTGCCAATGAATAA
Protein Properties
Pfam Domain Function:
Protein Residues:511
Protein Molecular Weight:55267
Protein Theoretical pI:11
Signaling Regions:
  • None
Transmembrane Regions:
  • 31-51
  • 90-110
  • 130-150
  • 159-179
  • 182-202
  • 237-257
  • 271-291
  • 314-334
  • 354-374
  • 384-404
  • 407-427
  • 443-463
  • 481-501
Protein Sequence:
>Virulence factor mviN homolog
MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAF
SQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADT
ADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIPAFAPTLLNISMIGFALFAAP
YFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPRINFHDAGAMRVVKQMGPAILGV
SVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNH
DEYNRLMDWGLRLCFLLALPSAVALGILSGPLTVSLFQYGKFTAFDALMTQRALIAYSVG
LIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLILTQLMNLAFIGPLKHAGLSLSIGLAACL
NASLLYWQLRKQKIFTPQPGWMAFLLRLVVAVLVMSGVLLGMLHIMPEWSLGTMPWRLLR
LMAVVLAGIAAYFAALAVLGFKVKEFARRTV
References
External Links:
ResourceLink
Uniprot ID:P0AF16
Uniprot Name:MVIN_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651515
Ecogene ID:EG13880
Ecocyc:EG13880
ColiBase:b1069
Kegg Gene:b1069
EchoBASE ID:EB3639
CCDB:MVIN_ECOLI
BacMap:16129032
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232