Probable phosphoribulokinase (P0AEX5)

Identification
Name:Probable phosphoribulokinase
Synonyms:
  • PRK
  • PRKase
  • Phosphopentokinase
Gene Name:prkB
Enzyme Class:
Biological Properties
General Function:Involved in ATP binding
Specific Function:ATP + D-ribulose 5-phosphate = ADP + D- ribulose 1,5-bisphosphate
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
  • Carbon fixation in photosynthetic organisms ec00710
  • Metabolic pathways eco01100
  • Microbial metabolism in diverse environments ec01120
KEGG Reactions:
1.0Thumb+1.0D-Ribulose 5-phosphate+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0D-Ribulose 5-phosphate + 1.0D-Ribulose 5-phosphate ↔ 1.0ADP + 1.0D-Ribulose 1,5-bisphosphate
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0D-Ribulose 5-phosphate → 1.0ADP + 1.0D-Ribulose 1,5-bisphosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB20145D-Ribulose 1,5-bisphosphateMetaboCard
ECMDB04148D-Ribulose 5-phosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
nucleoside binding
phosphoribulokinase activity
purine nucleoside binding
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b3355
Gene OrientationClockwise
Centisome Percentage:75.06
Left Sequence End3482512
Right Sequence End3483381
Gene Sequence:
>870 bp
ATGTCCATTTTAATCGATAAAAACACCAAGGTTATCTGCCAGGGCTTTACCGGTAGCCAG
GGGACTTTCCACTCAGAACAGGCCATTGCATACGGCACTAAAATGGTTGGCGGCGTAACC
CCAGGTAAAGGCGGCACCACCCACCTCGGCCTGCCGGTGTTCAACACCGTGCGTGAAGCC
GTTGCTGCCACTGGCGCTACCGCTTCTGTTATCTACGTACCAGCACCGTTCTGCAAAGAC
TCCATTCTGGAAGCCATCGACGCAGGCATCAAACTGATTATCACCATCACTGAAGGCATC
CCGACGCTGGATATGCTGACCGTGAAAGTGAAGCTGGATGAAGCAGGCGTTCGTATGATC
GGCCCGAACTGCCCAGGCGTTATCACTCCGGGTGAATGCAAAATCGGTATCCAGCCTGGT
CACATTCACAAACCGGGTAAAGTGGGTATCGTTTCCCGTTCCGGTACACTGACCTATGAA
GCGGTTAAACAGACCACGGATTACGGTTTCGGTCAGTCGACCTGTGTCGGTATCGGCGGT
GACCCGATCCCGGGCTCTAACTTTATCGACATTCTCGAAATGTTCGAAAAAGATCCGCAG
ACCGAAGCGATCGTGATGATCGGTGAGATCGGCGGTAGCGCTGAAGAAGAAGCAGCTGCG
TACATCAAAGAGCACGTTACCAAGCCAGTTGTGGGTTACATCGCTGGTGTGACTGCGCCG
AAAGGCAAACGTATGGGCCACGCGGGTGCCATCATTGCCGGTGGGAAAGGGACTGCGGAT
GAGAAATTCGCTGCTCTGGAAGCCGCAGGCGTGAAAACCGTTCGCAGCCTGGCGGATATC
GGTGAAGCACTGAAAACTGTTCTGAAATAA
Protein Properties
Pfam Domain Function:
Protein Residues:289
Protein Molecular Weight:32344
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Probable phosphoribulokinase
MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSFHRYTRPEMDMAIRKAR
DAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTPWQPL
PEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLEWIQKLIRDTSERGHSREAVM
DSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFAAKGIPSLDESFVVIHFRNLEGI
DFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIMLPLVQRLMEGKKIE
References
External Links:
ResourceLink
Uniprot ID:P0AEX5
Uniprot Name:KPPR_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651324
Ecogene ID:EG12365
Ecocyc:EG12365
ColiBase:b3355
Kegg Gene:b3355
EchoBASE ID:EB2268
CCDB:KPPR_ECOLI
BacMap:16131234
General Reference:
  • Bhasin, R., Freundlich, M. (1991). "The nucleotide sequence of the Escherichia coli crp divergent RNA and an overlapping ORF." Biochim Biophys Acta 1129:109-111. Pubmed: 1756168
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Borodovsky, M., Koonin, E. V., Rudd, K. E. (1994). "New genes in old sequence: a strategy for finding genes in the bacterial genome." Trends Biochem Sci 19:309-313. Pubmed: 7940673
  • Borodovsky, M., Rudd, K. E., Koonin, E. V. (1994). "Intrinsic and extrinsic approaches for detecting genes in a bacterial genome." Nucleic Acids Res 22:4756-4767. Pubmed: 7984428
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Robison, K., Gilbert, W., Church, G. M. (1994). "Large scale bacterial gene discovery by similarity search." Nat Genet 7:205-214. Pubmed: 7920643