| Identification |
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| Name: | Purine ribonucleoside efflux pump NepI |
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| Synonyms: | Not Available |
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| Gene Name: | nepI |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | purine nucleoside transmembrane transport |
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| Specific Function: | Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Transports: | |
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| Transport References: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| integral component of membrane | | plasma membrane | | purine nucleoside transmembrane transport | | purine nucleoside transmembrane transporter activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1191
atgagtgaatttattgccgaaaaccgcggcgcggatgccatcacccgaccgaactggtca
gccgttttctcggtggcgttttgtgtcgcctgtctgattatcgttgagtttttgcccgtc
agtttgttgacgccaatggcccaggatttaggcatttcggaaggggttgccgggcaatcg
gtgaccgtgaccgcctttgtggcaatgtttgccagtttgtttattacccagacaattcag
gctactgaccgccgctacgttgttattttgtttgccgttttgctgacgctctcctgcttg
ctggtttcctttgctaactcattcagtttgcttttaatcggtcgtgcctgtctggggctg
gcgctgggcgggttctgggcgatgtcggcgtcgctgaccatgcgtctggtgccgccgcgt
acggtgccgaaggcgctgtcggtgatcttcggcgcggtttctattgcgctggtgattgcc
gcgccgttgggcagttttttaggcgagcttatcggttggcgcaatgtctttaatgcggcg
gcggtgatgggcgtgctgtgtattttctggattatcaaatcattgccttcactgccaggc
gaaccctcgcatcagaaacaaaatactttccgcttattacaacgtccgggtgtgatggca
gggatgatcgccatcttcatgtctttcgccgggcagtttgctttcttcacgtatattcgc
ccggtgtatatgaacctggcgggattcggcgtggatggcttaacgctggtgctgttgagt
tttggtatcgccagctttattggtacgtcgctttcgtcgttcattcttaaacgttcggta
aaactggccttagcaggcgcgccgttaatactggctgtgagtgcgttggtactgacgttg
tggggaagcgataaaatcgttgctaccggcgtggcgattatctgggggctaacttttgca
ttggttcccgtcggctggtcaacgtggatcacccgctcgctggccgatcaggcagaaaaa
gccgggtctattcaggtggcggttattcagcttgctaatacctgtggcgcggcaatcggc
ggttatgcgctggataatattggtctgacttcgccgttgatgttgtccggcacattgatg
ttgctgactgcattgttggttactgcaaaggtgaaaatgaagaaatcctga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 396 |
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| Protein Molecular Weight: | 41841 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | - 22-42
- 55-75
- 86-106
- 108-128
- 148-168
- 176-196
- 216-236
- 256-276
- 282-302
- 306-326
- 344-364
- 367-387
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| Protein Sequence: | >Purine ribonucleoside efflux pump NepI
MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQS
VTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGL
ALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAA
AVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIR
PVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTL
WGSDKIVATGVAIIWGLTFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAIG
GYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMKKS |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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