Fructoselysine 6-phosphate deglycase (P0AC00)

Identification
Name:Fructoselysine 6-phosphate deglycase
Synonyms:Not Available
Gene Name:frlB
Enzyme Class:Not Available
Biological Properties
General Function:Involved in carbohydrate binding
Specific Function:Catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
Cellular Location:Not Available
SMPDB Pathways:
  • Fructoselysine and Psicoselysine Degradation PW002049
KEGG Pathways:Not Available
SMPDB Reactions:
1.0Thumb+1.0Thumb ↔ 1.0β-D-glucose 6-phosphate+1.0Thumb
1.0Fructoselysine-6-phosphate + 1.0Water ↔ 1.0β-D-glucose 6-phosphate + 1.0L-Lysine
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Fructoselysine-6-phosphate + 1.0Water ↔ 1.0Glucose 6-phosphate + 1.0L-Lysine
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Fructoselysine-6-phosphate + 1.0Water → 1.0Glucose 6-phosphate + 1.0L-Lysine
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB20558Fructoselysine-6-phosphateMetaboCard
ECMDB01401Glucose 6-phosphateMetaboCard
ECMDB00182L-LysineMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
binding
carbohydrate binding
sugar binding
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b3371
Gene OrientationClockwise
Centisome Percentage:75.42
Left Sequence End3499290
Right Sequence End3500312
Gene Sequence:
>1023 bp
ATGAAAAAAGTGTTATTGATAATCTTGTTATTGCTGGTGGTACTGGGTATCGCCGCTGGT
GTGGGCGTCTGGAAGGTTCGCCATCTTGCCGACAGCAAATTGCTTATCAAAGAAGAGACG
ATATTTACCCTGAAGCCAGGGACCGGACGTCTGGCGCTCGGTGAACAGCTTTATGCCGAT
AAGATCATCAATCGTCCACGGGTTTTTCAATGGCTGCTGCGTATCGAACCGGATCTTTCT
CACTTTAAAGCCGGGACTTACCGCTTTACACCGCAGATGACCGTGCGCGAGATGCTGAAA
TTGCTGGAAAGCGGTAAAGAAGCACAGTTCCCTCTGCGACTGGTAGAAGGGATGCGTCTG
AGCGATTACCTCAAGCAATTGCGTGAGGCCCCGTATATCAAGCATACGCTGAGCGATGAT
AAGTACGCCACCGTAGCGCAGGCACTTGAACTGGAAAACCCGGAGTGGATTGAAGGTTGG
TTCTGGCCAGACACCTGGATGTATACCGCCAATACCACCGATGTCGCGTTACTCAAGCGA
GCGCACAAGAAAATGGTGAAAGCGGTCGATAGCGCCTGGGAAGGGCGTGCGGACGGTCTG
CCTTATAAAGATAAAAACCAGTTGGTGACGATGGCATCAATTATCGAAAAAGAAACCGCC
GTTGCCAGTGAACGCGATAAGGTTGCCTCAGTATTTATCAACCGTTTACGCATTGGTATG
CGCCTGCAGACCGACCCGACCGTGATTTACGGGATGGGAGAGCGTTATAATGGCAAACTT
TCTCGTGCAGACCTGGAAACGCCGACAGCGTATAACACCTATACCATTACCGGTCTGCCG
CCAGGTGCGATAGCGACGCCGGGGGCGGATTCGCTGAAGGCTGCTGCGCATCCGGCAAAA
ACGCCGTATCTCTATTTTGTGGCCGATGGTAAAGGTGGTCACACGTTTAATACCAATCTT
GCCAGTCATAACAAGTCTGTGCAGGATTATCTGAAAGTGCTTAAGGAAAAAAATGCGCAG
TAA
Protein Properties
Pfam Domain Function:
Protein Residues:340
Protein Molecular Weight:38569
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Fructoselysine 6-phosphate deglycase
MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACGSPLNAAQ
TAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALELGRACGA
LTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVVLEMITRLAPNAEIGKIKNDL
KQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLMEFTWTHGC
VIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDYAEISQGL
HPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYYGGLVEY
References
External Links:
ResourceLink
Uniprot ID:P0AC00
Uniprot Name:FRLB_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674836
Ecogene ID:EG12909
Ecocyc:EG12909
ColiBase:b3371
Kegg Gene:b3371
EchoBASE ID:EB2746
CCDB:FRLB_ECOLI
BacMap:162135909
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Wiame, E., Delpierre, G., Collard, F., Van Schaftingen, E. (2002). "Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli." J Biol Chem 277:42523-42529. Pubmed: 12147680