Ribosomal-protein-alanine acetyltransferase_ (P0A948)

Identification
Name:Ribosomal-protein-alanine acetyltransferase_
Synonyms:
  • Acetylating enzyme for N-terminal of ribosomal protein S5
Gene Name:rimJ
Enzyme Class:
Biological Properties
General Function:Involved in N-acetyltransferase activity
Specific Function:This enzyme acetylates the N-terminal alanine of ribosomal protein S5. Plays also a role in the temperature regulation of pap pilin transcription
Cellular Location:Cytoplasm
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
KEGG Reactions:
1.0Thumb+1.0Ribosomal-protein L-alanine ↔ 1.0Thumb+1.0Ribosomal-protein N-acetyl-L-alanine
1.0Acetyl-CoA + 1.0Ribosomal-protein L-alanine ↔ 1.0Coenzyme A + 1.0Ribosomal-protein N-acetyl-L-alanine
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB01206Acetyl-CoAMetaboCard
GO Classification:
Function
acetyltransferase activity
acyltransferase activity
catalytic activity
N-acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
metabolic process
Gene Properties
Blattner:b1066
Gene OrientationClockwise
Centisome Percentage:24.24
Left Sequence End1124785
Right Sequence End1125369
Gene Sequence:
>585 bp
ATGTTTGGCTATCGCAGTAACGTGCCAAAAGTGCGCTTAACCACAGACCGACTGGTCGTG
CGTCTGGTGCATGATCGTGATGCCTGGCGTCTTGCGGATTATTACGCAGAGAATCGCCAT
TTCCTCAAGCCCTGGGAGCCAGTGCGCGACGAAAGCCACTGTTATCCATCAGGCTGGCAG
GCCAGGCTGGGGATGATTAACGAATTTCATAAACAAGGTTCAGCTTTCTACTTTGGCTTA
TTCGACCCGGACGAAAAAGAGATTATTGGCGTTGCCAATTTTTCCAATGTTGTTCGTGGC
TCTTTTCATGCCTGCTATCTCGGTTATTCGATTGGGCAAAAATGGCAGGGCAAAGGACTC
ATGTTTGAAGCCCTGACCGCAGCCATTCGTTATATGCAGCGCACCCAACATATTCATCGC
ATTATGGCTAATTATATGCCGCACAATAAACGCAGCGGTGATTTACTGGCGCGACTGGGT
TTTGAAAAAGAAGGCTATGCGAAAGACTATCTGTTGATTGATGGACAATGGCGCGATCAC
GTACTGACGGCATTAACTACCCCAGACTGGACGCCCGGCCGCTAA
Protein Properties
Pfam Domain Function:
Protein Residues:194
Protein Molecular Weight:22688
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Ribosomal-protein-alanine acetyltransferase
MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKPWEPVRDESHCYPSGWQ
ARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSFHACYLGYSIGQKWQGKGL
MFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLGFEKEGYAKDYLLIDGQWRDH
VLTALTTPDWTPGR
References
External Links:
ResourceLink
Uniprot ID:P0A948
Uniprot Name:RIMJ_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651524
Ecogene ID:EG10851
Ecocyc:EG10851
ColiBase:b1066
Kegg Gene:b1066
EchoBASE ID:EB0844
CCDB:RIMJ_ECOLI
BacMap:16129029
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • White-Ziegler, C. A., Low, D. A. (1992). "Thermoregulation of the pap operon: evidence for the involvement of RimJ, the N-terminal acetylase of ribosomal protein S5." J Bacteriol 174:7003-7012. Pubmed: 1356970
  • Yoshikawa, A., Isono, S., Sheback, A., Isono, K. (1987). "Cloning and nucleotide sequencing of the genes rimI and rimJ which encode enzymes acetylating ribosomal proteins S18 and S5 of Escherichia coli K12." Mol Gen Genet 209:481-488. Pubmed: 2828880