Putative sialic acid transporter (Q8X9G8)

Identification
Name:Putative sialic acid transporter
Synonyms:
  • Sialic acid permease
Gene Name:nanT
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transmembrane transport
Specific Function:May be a sugar-cation symporter involved in sialic acid uptake
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Function
carbohydrate transmembrane transporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
establishment of localization
transmembrane transport
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1491 bp
ATGGTGGCGGTGATTTATGCACCGCTGATCCCGGCAGCTCTCACGCTGATATCGCCTGCT
TTGTCGTTGACACACTGGCAGGCGTTATTTGCCGATCCACAGTTACCGCAGGCATTACTG
GCAACGCTGGTGTCGACAACCATCGCGGCGGTCGGGGCGTTGTTGATTGCCCTACTGGTG
ATTGTGGCGCTGTGGCCTGGGCCGAAATGGCAGCGTATGTGCACCCGTCTGCCGTGGCTG
CTCGCCATTCCCCATGTGGCTTTTGCCACCAGCGCCCTTCTGCTCTTTGCTGACGGAGGG
CTGCTTTATGACTATTTCCCGTATTTCACTCCGCCAATGGACAAATTGGGTATTGGGCTG
GGCTTCACGCTGGCGGTGAAAGAAAGCGCATTTCTGCTGTGGATCTTAGCAGCGGTATTG
AGTGAAAAACGGCTTTTACAGCAAGTCATCGTGCTGGATTCGCTGGGCTACAGCCGCTGG
CAATGCCTGAACTGGCTGCTGTTGCCCTCCGTCGCGCCTGCGCTGGCAATGGCGATGCTG
GCGATTGTTGCCTGGTCGCTGTCGGTCGTAGATGTGGCGATTATTCTTGGGCCAGGTAAT
CCACCGACGCTGGCAGTAATTAGCTGGCAGTGGTTAACTCAGGGCGACGCCGATCAACAA
ACGAAAGGCGCACTCGCCAGCCTGCTGCTGATGTTGTTACTCGCCGCCTACGTTTTGCTG
GGCTATCTGCTATGGTGTACCTGGCGGCGTACTATTCCCCGCGTAGATGGCGTTCGTAAG
CCTGCCACGCCTTTATTGCCAGGCATTACGCTGGCGAGTTTTTTACCCTTGACCAGTGTG
CTGTGTGTGGTTCTGCTGGCGATCCTCGCGGATCAGTCGACGATCAATAGTGAAGCGCTC
ATCAACAGCCTGACAATGGGGCTGGTGGCGACATTCATCGCTTTGCTCCTGTTACTGCTG
TGGCTGGAATGGGGGCCACAGCGTCGCCAGTTGTGGCTATGGTTGCCGATTTTATTACCG
GCACTGCCGCTGGTGGCGGGCCAGTACACGCTGGCGCTATGGCTGAACATGGATGGAAGC
TGGACGGCGGTGGTCTGGGGGCATCTGCTGTGGGTAATGCCGTGGATGCTGTTTATCCTG
CAACCCGCCTGGCAGCGCATTGATTCACGGTTAATTTTGATTGCACAAACACTGGGCTGG
TCGCGGGCCAAAATCTTCTTTTACGTGAAATGTCCGCTTATGCTACGCCCTACGCTGATT
GCCTTCGCGGTGGGATTTTCAGTCAGTATTGCGCAGTATATGCCGACGCTGTGGCTGGGC
GCGGGGCGTTTTCCGACGCTCACCACTGAGGCGGTGGCATTAAGCAGCGGCGGCAGCAAC
GGTATTCTCGCCGCCCTGGCTTTATGGCAACTGCTATTACCGCTTATTATTTTTGCCCTG
ACCGCGTTAGTCGCAAAATGGGTAGGTTATGTCAGACAAGGACTCCGCTAA
Protein Properties
Pfam Domain Function:
Protein Residues:496
Protein Molecular Weight:53611
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • 22-42
  • 58-78
  • 92-112
  • 148-168
  • 170-190
  • 224-244
  • 247-267
  • 278-298
  • 313-333
  • 355-375
  • 406-426
  • 431-451
Protein Sequence:
>Putative sialic acid transporter
MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASL
ISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGM
GMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIG
ILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFC
FAGNLQNAAIVAVLGLLCTAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPT
YLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFA
IGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPI
IGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSG
AVPFGSAKNDLVKTKS
References
External Links:
ResourceLink
Uniprot ID:Q8X9G8
Uniprot Name:NANT_ECO57
GenBank Gene ID:AE005174
Genebank Protein ID:12515777
EchoBASE ID:EB4145
CCDB:NANT_ECO57
General Reference:
  • Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
  • Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551