| Identification |
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| Name: | Probable deoxycholate-binding periplasmic protein YgiS |
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| Synonyms: | Not Available |
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| Gene Name: | ygiS |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | transmembrane transport |
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| Specific Function: | Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP-binding cassette (ABC) transporter complex | | periplasmic space | | transmembrane transport |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1608
atgtatacgcgaaatttattatggctggtcagcctggtaagtgcggctcctctctacgct
gctgacgttcccgccaacacaccgctcgccccgcaacaagtctttcgttacaacaatcat
agcgacccaggtacgctcgacccgcaaaaggtggaggagaatactgccgcgcagattgtg
ctggatctgtttgaaggtctggtatggatggacggtgaaggccaggtgcagcccgctcag
gctgaacgctgggagatactggacggcggcaagcgctatattttccatctgcgtagcggt
ttgcagtggtccgacggtcagcctctgacggcagaggattttgtcctcggctggcagcgc
gcggttgacccgaaaacggcaagcccttttgctggctatctggcacaggcgcacattaac
aatgccgcagctattgttgcgggtaaagcagatgttacatcgctgggtgtcaaagcgacg
gatgatcgtactcttgaagttacgcttgagcagccggttccttggttcacgacgatgctc
gcctggccgacgctgttcccggttcctcatcatgtcatcgctaaacatggcgatagctgg
agtaagccagagaacatggtttacaacggtgcctttgtgcttgatcagtgggtagttaac
gaaaagattactgcacgcaaaaatccaaagtaccgcgatgcgcaacatacagtattgcaa
caggttgagtatctggcgctagataattcggtcaccggctataaccgctatcgcgcggga
gaggtcgatctcacctgggttccggcgcagcaaattcccgccattgaaaaatcactgcct
ggcgagctacgaattattccgcgtctgaacagcgaatattacaacttcaaccttgagaaa
ccgccatttaacgatgtgcgagtgcgtcgggcgctatatcttacggttgatcgacagctt
attgcgcaaaaggtactggggttgagaacgcccgcaaccacgctgacgccgccagaggta
aaaggctttagcgcgacgacgttcgatgaactgcaaaagccaatgagtgagcgcgtcgcg
atggcaaaagccttgctgaaacaggcgggatacgacgcctctcatccgctacgctttgag
ctgttctacaacaagtacgatctgcatgaaaagaccgcgatagcgttgtcttccgaatgg
aaaaaatggctgggtgcacaggtgacgctgcgcacaatggagtggaaaacctatcttgat
gcccgacgagccggtgatttcatgctgtctcggcagtcgtgggatgcgacgtacaatgat
gcttccagcttcctgaacacgctcaaaagcgatagtgaagaaaacgtcggtcactggaaa
aatgcgcagtatgacgccttactaaaccaggccacgcagatcactgatgcgacaaagcgt
aatgcgttgtatcagcaggcagaagtgatcatcaaccaacaggcaccgctgattcctatc
tactatcagccgttaatcaaactgcttaaaccctacgttggcggttttccgctgcataat
ccccaggattatgtctacagcaaagagttgtatatcaaggcacattga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 535 |
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| Protein Molecular Weight: | 60693 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Probable deoxycholate-binding periplasmic protein YgiS
MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIV
LDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQWSDGQPLTAEDFVLGWQR
AVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKATDDRTLEVTLEQPVPWFTTML
AWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWVVNEKITARKNPKYRDAQHTVLQ
QVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIEKSLPGELRIIPRLNSEYYNFNLEK
PPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATTLTPPEVKGFSATTFDELQKPMSERVA
MAKALLKQAGYDASHPLRFELFYNKYDLHEKTAIALSSEWKKWLGAQVTLRTMEWKTYLD
ARRAGDFMLSRQSWDATYNDASSFLNTLKSDSEENVGHWKNAQYDALLNQATQITDATKR
NALYQQAEVIINQQAPLIPIYYQPLIKLLKPYVGGFPLHNPQDYVYSKELYIKAH |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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