ECMDB

Identification

Name:

Acetyl-CoA:oxalate CoA-transferase

Synonyms:

Not Available

Gene Name:

yfdE

Enzyme Class:

2.8.3.19

Biological Properties

General Function:

metabolic process

Specific Function:

Involved in the catabolism of oxalate and in the adapatation to low pH. ACOCT serves to prime the oxalate-induced acid tolerance response (ATR) cycle by producing substrate for oxalyl-CoA decarboxylase (OXC) and formyl-coenzyme A transferase (FCOCT). Catalyzes the reversible conversion of acetyl-CoA and oxalate to oxalyl-CoA and acetate. It can also use formyl-CoA and oxalate to produce oxalyl-CoA and formate with significantly reduced specific activity.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

KEGG Reactions:

1.0

↔

1.0

1.0Acetyl-CoA + 1.0Oxalic acid ↔ 1.0Acetic acid + 1.0Oxalyl-CoA
ReactionCard

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
acetyl-CoA:oxalate CoA-transferase
metabolic process

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>1146
atgacaaataatgaaagcaaagggccgtttgaaggcttattagttatcgatatgacacat
gtccttaatggacctttcggaactcaacttctttgtaatatgggcgcaagggtaattaaa
gttgagccgccgggtcatggtgatgatacccgcacatttggtccctatgtggatggacag
tcactctattacagttttattaatcatggcaaagagagtgtggttcttgatttaaagaat
gatcacgataaaagtatatttataaatatgctcaaacaagctgatgtattagctgagaat
tttcgcccaggtacaatggaaaaactggggttttcatgggaaacgcttcaagaaatcaac
ccgcgcctcatatatgcttcatcgtcaggtttcggacataccggtccgctaaaagatgct
cctgcctacgataccatcattcaggcaatgagcgggataatgatggaaacaggatatcct
gatgctccgccagtgcgcgttggtacatctcttgcggatctatgcggcggtgtctattta
ttcagcggaatagtgagtgcactttatggccgcgaaaagagccagagaggggcgcatgtc
gatatagcgatgtttgatgccacgctgagttttctggagcatggtctgatggcatatatc
gcaactgggaagtcaccacaacgtctgggaaatcgccatccctacatggcaccttttgat
gttttcaatactcaggataagccgattacgatttgttgtggtaatgacaagcttttttct
gcgttatgccaggcactggagcttacggaactggttaatgatccccgatttagcagcaat
attttacgcgtacaaaaccaggctattcttaaacaatatattgagcggacgttaaaaacg
caggcagctgaagtttggttagccagaatacatgaagttggtgtacccgtcgcgccgtta
ttaagtgtggctgaggccattaaattgccacaaactcaggcgagaaatatgttgattgaa
gccgggggaataatgatgccgggtaatccgataaaaatcagcggctgcgcggacccgcat
gttatgccgggagcggcaacgctcgaccagcatggggaacaaattcgccaggagttctca
tcataa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

381

Protein Molecular Weight:

41670

Protein Theoretical pI:

Not Available

PDB File:

4HL6

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Acetyl-CoA:oxalate CoA-transferase
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQ
SLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEIN
PRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRVGTSLADLCGGVYL
FSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
VFNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKT
QAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPH
VMPGAATLDQHGEQIRQEFSS

References

External Links:

Resource	Link
Uniprot ID:	P76518
Uniprot Name:	ACOCT_ECOLI
PDB ID:	4HL6
CCDB:	ACOCT_ECOLI

General Reference:

Not Available

Acetyl-CoA:oxalate CoA-transferase (P76518)