ECMDB

Identification

Name:

Metal-binding protein ZinT

Synonyms:

Not Available

Gene Name:

zinT

Enzyme Class:

Not Available

Biological Properties

General Function:

response to cadmium ion

Specific Function:

May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cadmium ion binding
cellular response to zinc ion starvation
cytoplasm
outer membrane-bounded periplasmic space
response to cadmium ion
zinc ion binding

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>651
ttggcgattcgtctttacaaactggctgttgctttaggtgtctttattgttagcgctcct
gccttttcgcatggtcatcactcacacggcaaacccttaacagaggtcgaacaaaaagct
gctaatggtgtttttgatgatgccaatgtacaaaaccgaacgctcagtgactgggatgga
gtctggcaatccgtttatcctttactgcaaagtggcaaacttgaccccgtctttcagaag
aaagcggatgcagataaaactaaaacatttgctgaaattaaagattattatcacaaaggt
tatgcaacagatatcgagatgattggcattgaggacggcattgttgaattccatagaaat
aatgaaacaacatcgtgtaaatatgattacgatggatacaaaatactcacctataaatca
ggcaagaaaggcgttcgttacttattcgaatgtaaagatcctgaaagcaaagcccctaaa
tatatacaatttagcgatcatataattgcaccacgaaaatcatctcattttcacattttt
atgggtaatgattcacagcaatctttattaaatgaaatggaaaactggccaacgtattat
ccatatcagttgagtagcgaagaagtggtcgaggaaatgatgtctcattga

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

216

Protein Molecular Weight:

24761

Protein Theoretical pI:

Not Available

PDB File:

1OEE

Signaling Regions:

1-23

Transmembrane Regions:

Not Available

Protein Sequence:

>Metal-binding protein ZinT
MAIRLYKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGVFDDANVQNRTLSDWDG
VWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHRN
NETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPKYIQFSDHIIAPRKSSHFHIF
MGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH

References

External Links:

Resource	Link
Uniprot ID:	P76344
Uniprot Name:	ZINT_ECOLI
PDB ID:	1OEE
CCDB:	ZINT_ECOLI

General Reference:

Not Available

Metal-binding protein ZinT (P76344)