Identification
Name:Metal-binding protein ZinT
Synonyms:Not Available
Gene Name:zinT
Enzyme Class:Not Available
Biological Properties
General Function:response to cadmium ion
Specific Function:May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cadmium ion binding
cellular response to zinc ion starvation
cytoplasm
outer membrane-bounded periplasmic space
response to cadmium ion
zinc ion binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>651
ttggcgattcgtctttacaaactggctgttgctttaggtgtctttattgttagcgctcct
gccttttcgcatggtcatcactcacacggcaaacccttaacagaggtcgaacaaaaagct
gctaatggtgtttttgatgatgccaatgtacaaaaccgaacgctcagtgactgggatgga
gtctggcaatccgtttatcctttactgcaaagtggcaaacttgaccccgtctttcagaag
aaagcggatgcagataaaactaaaacatttgctgaaattaaagattattatcacaaaggt
tatgcaacagatatcgagatgattggcattgaggacggcattgttgaattccatagaaat
aatgaaacaacatcgtgtaaatatgattacgatggatacaaaatactcacctataaatca
ggcaagaaaggcgttcgttacttattcgaatgtaaagatcctgaaagcaaagcccctaaa
tatatacaatttagcgatcatataattgcaccacgaaaatcatctcattttcacattttt
atgggtaatgattcacagcaatctttattaaatgaaatggaaaactggccaacgtattat
ccatatcagttgagtagcgaagaagtggtcgaggaaatgatgtctcattga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:216
Protein Molecular Weight:24761
Protein Theoretical pI:Not Available
PDB File:1OEE
Signaling Regions:
  • 1-23
Transmembrane Regions:Not Available
Protein Sequence:
>Metal-binding protein ZinT
MAIRLYKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGVFDDANVQNRTLSDWDG
VWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHRN
NETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPKYIQFSDHIIAPRKSSHFHIF
MGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH
References
External Links:
ResourceLink
Uniprot ID:P76344
Uniprot Name:ZINT_ECOLI
PDB ID:1OEE
CCDB:ZINT_ECOLI
General Reference:Not Available