| Identification |
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| Name: | Murein DD-endopeptidase MepH |
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| Synonyms: | Not Available |
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| Gene Name: | mepH |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | peptidoglycan turnover |
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| Specific Function: | A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| capsule polysaccharide biosynthetic process | | cell wall organization | | cysteine-type peptidase activity | | endopeptidase activity | | peptidoglycan metabolic process | | peptidoglycan turnover |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >816
gtggcgcggataaaccgtatttcgatcacgctctgtgctttactttttaccaccctgcct
ttaacgcctatggcccatgcttcaaagcaagccagggagagttctgctaccactcatatc
accaaaaaagcagataaaaagaaaagcacggcaaccaccaaaaagacccagaaaacagcg
aaaaaagccgccagtaaaagtacgaccaaaagcaaaaccgcttcttccgttaaaaaatct
tccattaccgcttctaaaaacgccaaaactcgcagcaaacacgccgtcaataaaacggcc
tcagccagctttaccgaaaagtgtaccaaacgtaagggctataaatcgcattgtgtgaaa
gtcaaaaatgccgcgtcaggaactcttgccgacgcgcacaaagcgaaggtgcaaaaagct
acgaaagtggcaatgaataaactgatgcagcaaattggtaagccatatcgttggggtggc
agctcaccgcgtaccggttttgattgcagcggcctggtttattacgcttataaagatttg
gtgaaaattcgtattccgcgtacggcgaatgaaatgtatcacctgcgtgatgcagcgcca
atcgaacgtagtgaactgaaaaacggcgacctggtctttttccgtactcagggacgcggc
acagccgatcatgtcggcgtgtatgtcggcaacggcaaatttattcagtcaccgcgcaca
ggtcaggaaattcaaatcacttctctcagtgaagactactggcagcgccactatgttggc
gctcgtcgggtaatgaccccaaaaacacttcgctaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 271 |
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| Protein Molecular Weight: | 29916 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Murein DD-endopeptidase MepH
MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKADKKKSTATTKKTQKTA
KKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASASFTEKCTKRKGYKSHCVK
VKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGGSSPRTGFDCSGLVYYAYKDL
VKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRT
GQEIQITSLSEDYWQRHYVGARRVMTPKTLR |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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