K(+)/H(+) antiporter NhaP2 (P76007)

Identification
Name:K(+)/H(+) antiporter NhaP2
Synonyms:Not Available
Gene Name:cvrA
Enzyme Class:Not Available
Biological Properties
General Function:regulation of potassium ion transport
Specific Function:K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels (By similarity). Participates in control of cell volume in low-osmolarity conditions.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell volume homeostasis
flavin adenine dinucleotide binding
integral component of membrane
integral component of plasma membrane
oxidoreductase activity, acting on CH-OH group of donors
potassium channel regulator activity
potassium:proton antiporter activity
regulation of potassium ion transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1737
ttggatgccacaacaataattagccttttcatcttaggatccatccttgtcaccagcagt
atattacttagttcattttcttcccgtcttggcattcctattctggttatttttctggcg
atcggcatgctggcaggagtcgatggcgtcggcggtatcccgtttgataattaccccttc
gcctacatggtaagtaacctggcactggcgattattttgctcgacggcgggatgcgcact
caggccagttcctttcgtgtggcgttaggaccggcactgtcgctggcgacgctgggcgtg
cttatcacctctggtttaaccggcatgatggcggcgtggctgtttaatcttgatttgatt
gaaggcttattaatcggcgctatcgtcggctctaccgatgctgcagcggtcttttctctg
ctgggtggtaaggggcttaacgaacgtgttggctcgacgctggaaattgaatccggcagt
aatgatccaatggcggtctttctgacgattaccctaattgcgatgatccagcatcatgag
agcaatattagctggatgttcattgtcgatattctgcaacaatttggtctgggcattgta
ataggtcttggcggcggttatttactactgcaaatgatcaaccgcatcgccctgcccgcc
ggattatatccattgctggcattaagtggcggtattctgattttctcattaactactgcg
ctggaaggtagcggtattctggcggtgtatctgtgcggttttctgctgggtaatcgccct
attcgcaaccgctacggcatcctgcaaaatttcgacggcctcgcctggctggcgcaaatc
gccatgttcctggtgctggggctgttggttaacccaagcgatctgctgcctattgccatt
ccggcgctcattttgtccgcatggatgatattcttcgcccgtcccctttcggtatttgct
ggattgctccccttccgcggtttcaatctgcgtgagcgcgtgtttatcagctgggtagga
ttacgcggcgcggtgccaatcatcctggccgtgttcccgatgatggcggggctggagaat
gcacgtctgttctttaatgtcgccttctttgtggttctggtttcactgctcttgcaggga
acatcactctcgtgggcggctaaaaaagccaaagtggtggttccgccagtgggacgtccg
gtgtcacgcgttggcctggatattcatccggaaaatccgtgggagcagtttgtttatcaa
ttgagtgccgataaatggtgcgtgggcgcggcactgcgcgatttgcatatgccaaaagag
acgcgtattgcggcactgtttcgtgataaccagttgcttcatcctaccggcagcacccga
ctgcgcgaaggcgatgtgttgtgtgtaattggtcgggaacgcgatcttccggcgctcggt
aaactgttcagccagtcgccgccggtcgcgctggatcaacgcttctttggtgacttcatt
ctcgaagccagcgccaaatatgctgatgttgcgctgatatatggcctggaagacgggcga
gaatatcgtgataagcagcaaacgctgggtgaaattgtccagcagttgttaggcgcggca
ccggttgtcggtgaccaggtagagtttgccgggatgatctggacggtggccgagaaagaa
gataatgaagtgttgaagattggcgtacgggtggctgaagaggaagctgaatcttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:578
Protein Molecular Weight:62284
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 6-26
  • 30-50
  • 58-78
  • 87-107
  • 119-141
  • 156-176
  • 183-203
  • 216-236
  • 237-257
  • 270-290
  • 293-313
  • 334-354
  • 363-383
Protein Sequence:
>K(+)/H(+) antiporter NhaP2
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPF
AYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLI
EGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQHHE
SNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFSLTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAI
PALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLEN
ARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQ
LSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAA
PVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES
References
External Links:
ResourceLink
Uniprot ID:P76007
Uniprot Name:NHAP2_ECOLI
CCDB:NHAP2_ECOLI
General Reference:Not Available