Identification
Name:Multidrug resistance protein MdtH
Synonyms:Not Available
Gene Name:mdtH
Enzyme Class:Not Available
Biological Properties
General Function:transmembrane transport
Specific Function:Confers resistance to norfloxacin and enoxacin.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
integral component of membrane
plasma membrane
response to antibiotic
transmembrane transport
transporter activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1209
atgtcccgcgtgtcgcaggcgaggaacctgggtaaatatttcctgctcatcgataatatg
ctggtcgtgctggggttctttgttgtcttcccgctgatctctatccgcttcgttgatcaa
atgggctgggccgccgtcatggtcggtattgctctcggtctacgccaatttattcagcaa
ggtctgggtattttcggcggtgcaattgccgaccgctttggtgccaaaccgatgattgtt
accggtatgctgatgcgcgccgccggattcgccacaatgggtatcgcccacgaaccgtgg
ctattgtggttttcatgcctgctctcgggactcggtggcacgttgtttgatccgccgcgt
tcggcgctggtggtgaaattaatccgtccacagcagcgtggtcgttttttctcgctgttg
atgatgcaggacagtgccggtgcggtcattggcgcattgttggggagctggctgttgcaa
tacgactttcgcctggtctgcgccacaggggcagttctatttgtgctatgtgcggcgttc
aatgcgtggttgttaccagcatggaaactctccaccgtacgcacgcccgttcgcgaaggc
atgacccgcgtgatgcgtgacaagcgttttgtcacctatgttctgacgctggcgggttac
tacatgctggctgtacaagtgatgctgatgctgccaattatggtcaacgacgtggctggc
gcgccctctgccgttaaatggatgtatgccattgaagcgtgtctgtcgttaacgttgctc
taccctatcgcccgctggagtgaaaagcattttcgtctggaacaccggttgatggctggg
ctgttgataatgtcattaagcatgatgccggtgggcatggtcagcggcctgcaacaactt
ttcaccctgatttgtctgttttatatcgggtcgatcattgccgagcctgcgcgtgaaacc
ttaagtgcttcgctggcggacgcaagagctcgcggcagctatatggggtttagccgtctg
ggtctggcgattggcggcgctattggttatatcggtggcggctggctgtttgacctgggc
aaatcggcgcaccagccagagcttccgtggatgatgctgggcattattggcatcttcact
ttccttgcgctgggttggcagtttagccagaaacgcgccgcgcgtcgtttgcttgaacgc
gacgcctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:402
Protein Molecular Weight:44362
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 13-33
  • 99-116
  • 139-159
  • 165-185
  • 214-234
  • 244-264
  • 277-297
  • 300-320
  • 340-360
  • 368-388
Protein Sequence:
>Multidrug resistance protein MdtH
MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQ
GLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPR
SALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAF
NAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAG
APSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQL
FTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLG
KSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA
References
External Links:
ResourceLink
Uniprot ID:P69367
Uniprot Name:MDTH_ECOLI
CCDB:MDTH_ECOLI
General Reference:Not Available