ECMDB

Identification

Name:

Autoinducer 2-degrading protein LsrG

Synonyms:

Not Available

Gene Name:

lsrG

Enzyme Class:

Not Available

Biological Properties

General Function:

metabolic process

Specific Function:

Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5-dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound.

Cellular Location:

Not Available

SMPDB Pathways:

Quorum Sensing PW000836

KEGG Pathways:

Not Available

SMPDB Reactions:

1.0(4S)-4-hydroxy-2,3-pentanedione 5-phosphate

1.0

→

1.03-hydroxy-2,4-pentanedione 5-phosphate

1.0

1.0(4S)-4-hydroxy-2,3-pentanedione 5-phosphate + 1.0(4S)-4-hydroxy-2,3-pentanedione 5-phosphate → 1.03-hydroxy-2,4-pentanedione 5-phosphate + 1.03-hydroxy-2,4-pentanedione 5-phosphate
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB24233	(4S)-4-hydroxy-2,3-pentanedione 5-phosphate	MetaboCard
ECMDB24234	3-hydroxy-2,4-pentanedione 5-phosphate	MetaboCard

GO Classification:

Function
catalytic activity
cytoplasm
metabolic process

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>291
atgcacgtcacactggttgaaattaacgttcatgaagacaaggttgacgagtttatcgaa
gtttttcgccagaaccacctgggctctgtacaggaagaaggcaatttgcgcttcgatgtc
ttacaggacccggaagtgaattcgcgcttttatatctacgaagcctataaagatgaagac
gcagtggcgttccataaaaccacgccccactacaaaacctgtgtcgcgaaactggaatct
ttaatgaccgggccgcgtaaaaaacgtctgttcaatggtttgatgccgtga

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

Protein Molecular Weight:

11254

Protein Theoretical pI:

Not Available

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Autoinducer 2-degrading protein LsrG
MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDPEVNSRFYIYEAYKDED
AVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP

References

External Links:

Resource	Link
Uniprot ID:	P64461
Uniprot Name:	LSRG_ECOLI
CCDB:	LSRG_ECOLI

General Reference:

Not Available

Autoinducer 2-degrading protein LsrG (P64461)