ECMDB

Identification

Name:

Outer-membrane lipoprotein carrier protein

Synonyms:

Not Available

Gene Name:

lolA

Enzyme Class:

Not Available

Biological Properties

General Function:

lipoprotein transport

Specific Function:

Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.May act as a regulator of the RCS-phosphorelay signal transduction pathway.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
chaperone-mediated protein transport across periplasmic space
lipoprotein localization to outer membrane
lipoprotein transport
lipoprotein transporter activity
outer membrane-bounded periplasmic space

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>612
atgaaaaaaattgccatcacctgtgcattactctcaagcttagtagcaagcagcgtttgg
gctgatgccgcaagcgatctgaaaagccgcctggataaagtcagcagcttccacgccagc
ttcacacaaaaagtgactgacggtagcggcgcggcggtgcaggaaggtcagggcgatctg
tgggtgaaacgtccaaacttattcaactggcatatgacacaacctgatgaaagcattctg
gtttctgacggtaaaacactgtggttctataacccgttcgttgagcaagctacggcaacc
tggctgaaagatgccaccggtaatacgccgtttatgctgattgcccgcaaccagtccagc
gactggcagcagtacaatatcaaacagaatggcgatgactttgtcctgacgccgaaagcc
agcaatggcaatctgaagcagttcaccattaacgtgggacgtgatggcacaatccatcag
tttagcgcggtggagcaggacgatcagcgcagcagttatcaactgaaatcccagcaaaat
ggggctgtggatgcagcgaaatttaccttcaccccgccgcaaggcgtcacggtagatgat
caacgtaagtag

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

203

Protein Molecular Weight:

22496

Protein Theoretical pI:

Not Available

PDB File:

1IWL

Signaling Regions:

1-21

Transmembrane Regions:

Not Available

Protein Sequence:

>Outer-membrane lipoprotein carrier protein
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDL
WVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSS
DWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQN
GAVDAAKFTFTPPQGVTVDDQRK

References

External Links:

Resource	Link
Uniprot ID:	P61316
Uniprot Name:	LOLA_ECOLI
PDB ID:	1IWL
CCDB:	LOLA_ECOLI

General Reference:

Not Available

Outer-membrane lipoprotein carrier protein (P61316)