| Identification |
|---|
| Name: | 50S ribosomal protein L2 |
|---|
| Synonyms: | Not Available |
|---|
| Gene Name: | rplB |
|---|
| Enzyme Class: | Not Available |
|---|
| Biological Properties |
|---|
| General Function: | translation |
|---|
| Specific Function: | One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G. |
|---|
| Cellular Location: | Not Available |
|---|
| SMPDB Pathways: | Not Available |
|---|
| KEGG Pathways: | |
|---|
| Metabolites: | |
|---|
| GO Classification: | | Function |
|---|
| cytosolic large ribosomal subunit | | rRNA binding | | structural constituent of ribosome | | transferase activity | | translation | | zinc ion binding |
|
|---|
| Gene Properties |
|---|
| Blattner: | Not Available |
|---|
| Gene Orientation | Not Available |
|---|
| Centisome Percentage: | Not Available |
|---|
| Left Sequence End | Not Available |
|---|
| Right Sequence End | Not Available |
|---|
| Gene Sequence: | >822
atggcagttgttaaatgtaaaccgacatctccgggtcgtcgccacgtagttaaagtggtt
aaccctgagctgcacaagggcaaaccttttgctccgttgctggaaaaaaacagcaaatcc
ggtggtcgtaacaacaatggccgtatcaccactcgtcatatcggtggtggccacaagcag
gcttaccgtattgttgacttcaaacgcaacaaagacggtatcccggcagttgttgaacgt
cttgagtacgatccgaaccgttccgcgaacatcgcgctggttctgtacaaagacggtgaa
cgccgttacatcctggcccctaaaggcctgaaagctggcgaccagattcagtctggcgtt
gatgctgcaatcaaaccaggtaacaccctgccgatgcgcaacatcccggttggttctact
gttcataacgtagaaatgaaaccaggtaaaggcggtcagctggcacgttccgctggtact
tacgttcagatcgttgctcgtgatggtgcttatgtcaccctgcgtctgcgttctggtgaa
atgcgtaaagtagaagcagactgccgtgcaactctgggcgaagttggcaatgctgagcat
atgctgcgcgttctgggtaaagcaggtgctgcacgctggcgtggtgttcgtccgaccgtt
cgcggtaccgcgatgaacccggtagaccacccacatggtggtggtgaaggtcgtaacttt
ggtaagcacccggtaactccgtggggcgttcagaccaaaggtaagaagacccgcagcaac
aagcgtactgataaattcatcgtacgtcgccgtagcaaataa |
|---|
| Protein Properties |
|---|
| Pfam Domain Function: | Not Available |
|---|
| Protein Residues: | 273 |
|---|
| Protein Molecular Weight: | 29860 |
|---|
| Protein Theoretical pI: | Not Available |
|---|
| PDB File: | 2J28 |
| Signaling Regions: | Not Available |
|---|
| Transmembrane Regions: | Not Available |
|---|
| Protein Sequence: | >50S ribosomal protein L2
MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQ
AYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGV
DAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGE
MRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNF
GKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK |
|---|
| References |
|---|
| External Links: | |
|---|
| General Reference: | Not Available |
|---|
