H(+)/Cl(-) exchange transporter ClcA (P58244)
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| Name: | H(+)/Cl(-) exchange transporter ClcA | ||||||||||||||||||||
| Synonyms: | Not Available | ||||||||||||||||||||
| Gene Name: | clcA | ||||||||||||||||||||
| Enzyme Class: | Not Available | ||||||||||||||||||||
| Biological Properties | |||||||||||||||||||||
| General Function: | Involved in ion channel activity | ||||||||||||||||||||
| Specific Function: | Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response | ||||||||||||||||||||
| Cellular Location: | Cell inner membrane; Multi-pass membrane protein (Probable) | ||||||||||||||||||||
| SMPDB Pathways: | Not Available | ||||||||||||||||||||
| KEGG Pathways: | Not Available | ||||||||||||||||||||
| Metabolites: |
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| GO Classification: |
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| Gene Properties | |||||||||||||||||||||
| Blattner: | Not Available | ||||||||||||||||||||
| Gene Orientation | Not Available | ||||||||||||||||||||
| Centisome Percentage: | Not Available | ||||||||||||||||||||
| Left Sequence End | Not Available | ||||||||||||||||||||
| Right Sequence End | Not Available | ||||||||||||||||||||
| Gene Sequence: | >1422 bp ATGAAAACTGATACTCCCTCTTTAGAAACACCGCAGGCCGCGCGCCTGCGACGCAGACAA CTGATTCGCCAACTTCTTGAGCGCGATAAAACCCCGTTAGCCATTTTGTTTATGGCGGCA GTCGTCGGCACGCTTGTCGGGCTGGCAGCGGTTGCTTTTGACAAAGGTGTCGCCTGGTTG CAGAACCAACGTATGGGGGCGCTGGTACATACTGCTGATAATTATCCGCTACTGTTAACC GTTGCTTTTCTCTGTTCGGCGGTGCTGGCGATGTTCGGCTACTTTTTGGTGCGCAAATAC GCGCCCGAAGCAGGGGGGTCGGGGATCCCGGAAATTGAAGGGGCGCTGGAAGATCAACGT CCTGTTCGCTGGTGGCGTGTATTGCCGGTGAAATTCTTTGGCGGGCTGGGGACACTCGGC GGAGGCATGGTGTTGGGGCGCGAAGGGCCAACCGTGCAGATCGGCGGTAATATCGGGCGG ATGGTACTCGATGTTTTCCGCCTGAAAGGTGATGAAGCTCGCCATACGCTGTTGGCAACC GGTGCGGCGGCGGGTCTGGCGGCGGCCTTTAACGCGCCGCTGGCGGGTATTTTGTTTATT ATCGAAGAGATGCGTCCGCAGTTTCGCTATACGTTAATTTCGATTAAAGCGGTATTTATT GSCGTCATTATGTCGACCATTATGTACCGGATTTTTAATCATGAAGTTGCGTTGATTGAC GTCGGTAAACTTTCTGACGCGCCGCTTAATACGCTGTGGCTTTATCTGATCCTCGGTATT ATTTTTGGCATTTTCGGCCCTATTTTTAATAAATGGGTGCTGGGGATGCAGGATTTGCTG CACCGTGTGCACGGTGGCAATATTACCAAATGGGTACTGATGGGTGGTGCGATTGGCGGT CTGTGTGGATTGCTGGGGTTTGTGGCACCAGCAACGTCGGGCGGCGGTTTTAACCTGATT CCTATCGCTACCGCGGGGAATTTCAGCATGGGAATGCTGGTGTTTATCTTCGTCGCGCGG GTCATTACCACCTTACTCTGCTTCTCTTCCGGCGCGCCGGGCGGTATTTTTGCCCCGATG CTGGCGCTGGGTACTGTGCTGGGAACCGCTTTCGGAATGGTTGCCGTTGAGCTGTTTCCG CAATATCACCTTGAGGCGGGGACGTTTGCTATTGCCGGAATGGGGGCGTTACTGGCGGCA TCTATTCGCGCGCCGTTAACGGGGATCATTCTGGTTCTGGAGATGACCGATAACTACCAG CTCATTTTGCCAATGATTATTACCGGTCTTGGCGCAACACTATTAGCGCAATTTACCGGC GGGAAACCGCTATACTCGGCGATTCTTGCGCGCACGCTGGCAAAACAGGAAGCTGAGCAA CTGGCGCGAAGCAAGGCCGCATCAGCCAGCGAGAATACTTGA | ||||||||||||||||||||
| Protein Properties | |||||||||||||||||||||
| Pfam Domain Function: |
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| Protein Residues: | 473 | ||||||||||||||||||||
| Protein Molecular Weight: | 50334 | ||||||||||||||||||||
| Protein Theoretical pI: | 10 | ||||||||||||||||||||
| PDB File: | 1KPK | ||||||||||||||||||||
| Signaling Regions: |
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| Transmembrane Regions: |
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| Protein Sequence: | >H(+)/Cl(-) exchange transporter ClcA MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWL QNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQR PVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDVFRLKGDEARHTLLAT GAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALID VGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGG LCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPM LALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQ LILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT | ||||||||||||||||||||
| References | |||||||||||||||||||||
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| General Reference: |
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