Serine/threonine-protein phosphatase 2 (P55799)

Identification
Name:Serine/threonine-protein phosphatase 2
Synonyms:Not Available
Gene Name:pphB
Enzyme Class:
Biological Properties
General Function:Involved in hydrolase activity
Specific Function:Has been shown, in vitro, to act on Ser, Thr and Tyr- phosphorylated substrates
Cellular Location:Cytoplasmic
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
KEGG Reactions:
1.0Thumb ↔ 1.0Thumb
1.0Water ↔ 1.0Phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21380Inorganic phosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
catalytic activity
hydrolase activity
Gene Properties
Blattner:b2734
Gene OrientationClockwise
Centisome Percentage:61.59
Left Sequence End2857782
Right Sequence End2858438
Gene Sequence:
>657 bp
GTGCAACGAGCGCGTTGTTATCTGATAGGTGAAACGGCGGTAGTGCTGGAACTGGAACCG
CCGGTGACGCTGGCTAGCCAGAAACGGATCTGGCGACTGGCGCAGCGTCTGGTGGATATG
CCGAATGTGGTTGAAGCCATTCCCGGCATGAACAATATCACGGTGATTTTGCGTAATCCT
GAGTCGCTGGCGCTGGATGCCATAGAGCGTTTGCAACGCTGGTGGGAGGAGAGCGAGGCG
CTGGAGCCGGAGTCTCGCTTTATTGAAATTCCGGTGGTTTACGGTGGTGCAGGCGGACCG
GATTTGGCGGTGGTCGCGGCGCATTGCGGGTTGAGCGAAAAACAGGTTGTTGAATTGCAC
TCCTCCGTGGAATACGTGGTCTGGTTTTTAGGTTTTCAACCGGGCTTCCCGTATCTCGGG
AGTTTGCCGGAACAACTACACACGCCACGGCGCGCTGAACCGCGCTTACTCGTTCCGGCA
GGTTCTGTCGGGATCGGCGGGCCGCAGACTGGTGTTTATCCGCTGGCAACGCCGGGTGGC
TGGCAGTTGATTGGTCATACCTCACTCAGCCTGTTTGATCCGGCGCGTGACGAACCCATC
TTATTACGTCCGGGAGACAGCGTGCGCTTTGTACCGCAGAAGGAGGGAGTATGCTGA
Protein Properties
Pfam Domain Function:
Protein Residues:218
Protein Molecular Weight:25098
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Serine/threonine-protein phosphatase 2
MPSTRYQKINAHHYRHIWVVGDIHGEYQLLQSRLHQLSFFPKIDLLISVGDNIDRGPESL
DVLRLLNQPWFTSVKGNHEAMALEAFETGDGNMWLASGGDWFFDLNDSEQQEAIDLLLKF
HHLPHIIEITNDNIKYAIAHADYPGSEYLFGKEIAESELLWPVDRVQKSLNGELQQINGA
DYFIFGHMMFDNIQTFANQIYIDTGSPNSGRLSFYKIK
References
External Links:
ResourceLink
Uniprot ID:P55799
Uniprot Name:PRP2_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:4062307
Ecogene ID:EG13102
Ecocyc:EG13102
ColiBase:b2734
Kegg Gene:b2734
EchoBASE ID:EB2905
CCDB:PRP2_ECOLI
BacMap:16130641
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Missiakas, D., Raina, S. (1997). "Signal transduction pathways in response to protein misfolding in the extracytoplasmic compartments of E. coli: role of two new phosphoprotein phosphatases PrpA and PrpB." EMBO J 16:1670-1685. Pubmed: 9130712