Identification
Name:p-hydroxybenzoic acid efflux pump subunit AaeB
Synonyms:Not Available
Gene Name:aaeB
Enzyme Class:Not Available
Biological Properties
General Function:transport
Specific Function:Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell. Substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
carboxylic acid transport
integral component of membrane
plasma membrane
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1968
atgggtattttctccattgctaaccaacatattcgctttgcggtaaaactggcgaccgcc
attgtactggcgctgtttgttggctttcacttccagctggaaacgccacgctgggcggta
ctgacagcggcgattgttgccgccggtacggcctttgctgcgggaggtgaaccgtattct
ggcgctattcgctatcgtggctttttgcgcatcatcggcacatttattggctgtattgcc
ggactggtgatcatcattgcgatgatccgcgcaccattattgatgattctggtgtgctgt
atctgggccggtttttgtacctggatatcctcgctggtacgaatagaaaactcgtatgcg
tgggggctggccggttataccgcgctgatcattgtgatcaccattcagccggaaccattg
cttacgccgcagtttgccgtcgaacgttgtagcgagatcgttatcggtattgtgtgtgcg
attatggcggatttgctcttttctccgcgatcgatcaaacaagaagtggatcgagagctg
gaaagtttgctggtcgcgcaatatcaattaatgcaactctgtatcaagcatggcgatggt
gaagttgtcgataaagcctggggcgacctggtgcgacgcaccacggcgctacaaggcatg
cgcagcaacctgaatatggaatcttcccgctgggcgcgggccaatcgacgtttaaaagcg
atcaatacgctatcgctgacgctgattacccaatcctgcgaaacttatcttattcagaat
acgcgcccggaattgatcactgatactttccgcgaattttttgacacgccggtagaaacc
gcgcaggacgtccacaagcagctcaaacgcctgcggagagttatcgcctggaccggggaa
cgggaaacgcctgtcaccatttatagctgggtcgcggcggcaacgcgttatcagcttctc
aagcgcggcgttatcagtaacacaaaaatcaacgccaccgaagaagagatcctgcaaggc
gaaccggaagtaaaagtagagtcagccgaacgtcatcatgcaatggttaacttctggcga
accacactttcctgcattctgggcacgcttttctggctgtggacgggctggacttccggc
agtggtgcaatggtgatgattgcggtagtgacgtcactggcaatgcgtttgccgaatcca
cgcatggtggcgatcgactttatctacgggacgctggccgcgctgccgttagggctgctc
tactttttggtgattatccctaatacccaacagagcatgttgctgctgtgcattagcctg
gcagtgctgggattcttcctcggtatagaagtacagaaacggcgactgggctcgatgggg
gcactggccagcaccataaatattatcgtgctggataacccgatgactttccatttcagt
cagtttctcgacagcgcattagggcaaatcgtcggctgtgtgctcgcgttcaccgttatt
ttgctggtgcgggataaatcgcgcgacaggaccggacgtgtactgcttaatcagtttgtt
tctgccgctgtttccgcgatgactaccaatgtggcacgtcgtaaagagaaccacctcccg
gcactttatcagcagctgtttttgctgatgaataagttcccaggggatttgccgaaattt
cgcctggcgctgacgatgattatcgcgcaccagcgcctgcgtgatgcaccgatcccggtt
aacgaggatttatcggcgtttcaccgacaaatgcgccgcacagcagaccatgtgatatct
gcccgtagcgatgataaacgtcgtcggtactttggccagttgctggaagaactggaaatc
taccaggaaaagctacgcatctggcaagcgccaccgcaggtgacggaaccggtaaatcgg
ctggcggggatgctccataagtatcaacatgcgttgaccgatagttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:655
Protein Molecular Weight:73590
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 13-33
  • 38-58
  • 69-89
  • 93-113
  • 121-141
  • 152-172
  • 370-390
  • 407-427
  • 431-451
  • 459-479
  • 482-502
Protein Sequence:
>p-hydroxybenzoic acid efflux pump subunit AaeB
MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGTAFAAGGEPYS
GAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYA
WGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDREL
ESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKA
INTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGE
RETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWR
TTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLL
YFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFS
QFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLP
ALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVIS
ARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVNRLAGMLHKYQHALTDS
References
External Links:
ResourceLink
Uniprot ID:P46481
Uniprot Name:AAEB_ECOLI
CCDB:AAEB_ECOLI
General Reference:Not Available