Protein TusB (P45530)

Identification
Name:Protein TusB
Synonyms:
  • tRNA 2-thiouridine synthesizing protein B
Gene Name:tusB
Enzyme Class:Not Available
Biological Properties
General Function:Not Available
Specific Function:Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
ECMDB202282-ThiouridineMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b3343
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>ENA|AAA58140|AAA58140.1 Escherichia coli str. K-12 substr. MG1655 hypothetical protein
ATGCTGCACACATTACATCGCTCACCCTGGCTGACGGATTTTGCTGCGCTGCTGCGTCTG
CTCAGTGAAGGAGACGAACTGCTATTATTGCAAGATGGCGTAACTGCCGCAGTTGACGGT
AACCGCTACCTTGAAAGTCTGCGTAATGCCCCCATTAAGGTCTATGCCCTGAACGAAGAC
CTTATTGCCCGCGGTTTGACTGGTCAAATTTCGAACGACATCATTCTCATTGACTATACT
GATTTCGTCAGACTTACGGTTAAGCACCCCAGCCAGATGGCCTGGTGA
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:Not Available
Protein Molecular Weight:Not Available
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>sp|P45530|TUSB_ECOLI Protein TusB OS=Escherichia coli (strain K12) GN=tusB PE=1 SV=1
MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNED
LIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW
References
External Links:
ResourceLink
Uniprot ID:P45530
ColiBase:b3343
Kegg Gene:b3343
BacMap:16131222
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Ikeuchi, Y., Shigi, N., Kato, J., Nishimura, A., Suzuki, T. (2006). "Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions." Mol Cell 21:97-108. Pubmed: 16387657
  • Numata, T., Fukai, S., Ikeuchi, Y., Suzuki, T., Nureki, O. (2006). "Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex." Structure 14:357-366. Pubmed: 16472754