ECMDB: ABC transporter ATP-binding protein uup (P43672)

Identification

Name:

ABC transporter ATP-binding protein uup

Synonyms:

Not Available

Gene Name:

uup

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in nucleotide binding

Specific Function:

Not Available

Cellular Location:

Cytoplasmic

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
ATPase activity
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
purine nucleoside binding
pyrophosphatase activity

Gene Properties

Blattner:

b0949

Gene Orientation

Clockwise

Centisome Percentage:

21.75

Left Sequence End

1009187

Right Sequence End

1011094

Gene Sequence:

>1908 bp
ATGTCATTAATCAGTATGCATGGCGCATGGCTGTCGTTCAGCGACGCGCCGCTTCTCGAT
AACGCAGAACTGCATATCGAAGATAACGAACGTGTTTGTCTGGTGGGCCGCAACGGCGCA
GGCAAATCGACGTTAATGAAAATCCTCAACCGTGAACAAGGGCTGGATGACGGTCGCATT
ATTTACGAGCAAGATTTGATTGTAGCGCGTCTGCAACAGGATCCGCCGCGTAACGTTGAG
GGTAGCGTTTATGATTTCGTTGCCGAAGGCATTGAAGAACAAGCGGAATATCTGAAACGC
TATCACGATATTTCGCGCCTGGTGATGAACGACCCGAGCGAGAAAAATCTCAACGAACTG
GCGAAGGTTCAGGAACAGCTGGATCACCACAACCTGTGGCAGCTGGAAAACCGCATCAAC
GAAGTGCTGGCGCAACTGGGGTTAGATCCTAACGTTGCGCTGTCGTCGCTTTCCGGCGGC
TGGTTGCGTAAAGCGGCATTAGGACGCGCGCTGGTGAGTAATCCGCGCGTGCTGTTGCTT
GATGAACCGACAAACCACCTGGATATTGAAACCATCGACTGGCTGGAAGGGTTTTTGAAA
ACTTTCAACGGGACGATTATTTTCATCTCCCACGACCGTTCGTTTATCCGCAATATGGCG
ACGCGCATTGTTGATCTCGATCGCGGCAAGCTGGTGACCTATCCAGGGAATTACGACCAG
TACCTGCTGGAAAAAGAAGAAGCCCTGCGCGTGGAAGAATTACAAAATGCCGAGTTCGAT
CGCAAACTGGCGCAGGAAGAGGTGTGGATCCGCCAGGGGATCAAAGCACGCCGTACCCGT
AATGAAGGCCGCGTACGCGCCCTGAAAGCGATGCGTCGCGAACGTGGTGAACGTCGCGAA
GTGATGGGTACCGCAAAGATGCAGGTGGAAGAGGCCAGCCGCTCCGGTAAAATCGTTTTC
GAAATGGAAGACGTTTGCTACCAGGTTAACGGTAAGCAACTGGTGAAAGATTTTTCTGCC
CAGGTTCTACGTGGCGACAAAATTGCCCTGATTGGTCCGAATGGGTGCGGCAAAACCACG
CTGCTAAAACTGATGCTCGGTCAGCTTCAAGCGGACAGCGGGCGTATTCACGTTGGCACC
AAACTGGAAGTGGCTTATTTCGATCAGCACCGCGCGGAACTGGATCCCGATAAAACGGTG
ATGGATAACCTTGCCGAAGGTAAGCAAGAGGTGATGGTTAACGGCAAGCCACGCCACGTA
TTGGGCTATTTGCAGGACTTTCTGTTCCATCCGAAACGGGCGATGACGCCGGTACGTGCG
CTTTCTGGCGGTGAGCGGAACCGCTTGCTGCTGGCGCGTTTGTTCCTCAAACCAAGCAAC
TTATTGATTCTTGACGAACCGACCAACGATCTTGATGTCGAAACGCTGGAACTGCTGGAA
GAACTGATCGACAGCTATCAGGGCACGGTATTGCTGGTTAGCCACGATCGTCAGTTTGTC
GATAACACCGTTACAGAATGTTGGATCTTCGAAGGCGGCGGTAAAATTGGTCGTTATGTC
GGCGGTTATCATGATGCCCGTGGTCAGCAAGAGCAGTATGTGGCGCTCAAACAGCCTGCG
GTGAAAAAAACCGAAGAAGCCGCCGCGGCAAAAGCAGAAACTGTAAAACGCAGCAGTAGC
AAACTAAGCTATAAATTGCAGCGCGAACTGGAGCAGCTACCGCAATTGCTCGAAGATCTG
GAGGCGAAGCTGGAAGCCCTACAGACGCAAGTGGCGGATGCTTCCTTCTTCAGTCAGCCG
CATGAGCAGACGCAAAAAGTGCTTGCTGATATGGCTGCTGCAGAGCAGGAGCTGGAGCAA
GCCTTTGAACGCTGGGAGTATCTTGAAGCGTTAAAAAATGGTGGCTGA

Protein Properties

Pfam Domain Function:

ABC_tran (PF00005 )

Protein Residues:

635

Protein Molecular Weight:

72066

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

None

Protein Sequence:

>ABC transporter ATP-binding protein uup
MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNREQGLDDGRI
IYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYHDISRLVMNDPSEKNLNEL
AKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGGWLRKAALGRALVSNPRVLLL
DEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRNMATRIVDLDRGKLVTYPGNYDQ
YLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKAMRRERGERRE
VMGTAKMQVEEASRSGKIVFEMEDVCYQVNGKQLVKDFSAQVLRGDKIALIGPNGCGKTT
LLKLMLGQLQADSGRIHVGTKLEVAYFDQHRAELDPDKTVMDNLAEGKQEVMVNGKPRHV
LGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLELLE
ELIDSYQGTVLLVSHDRQFVDNTVTECWIFEGGGKIGRYVGGYHDARGQQEQYVALKQPA
VKKTEEAAAAKAETVKRSSSKLSYKLQRELEQLPQLLEDLEAKLEALQTQVADASFFSQP
HEQTQKVLADMAAAEQELEQAFERWEYLEALKNGG

References

External Links:

Resource	Link
Uniprot ID:	P43672
Uniprot Name:	UUP_ECOLI
GenBank Gene ID:	AP009048
Genebank Protein ID:	4062519
Ecogene ID:	EG13134
Ecocyc:	EG13134
ColiBase:	b0949
Kegg Gene:	b0949
EchoBASE ID:	EB2933
CCDB:	UUP_ECOLI
BacMap:	16128916

General Reference:

Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
Koh, Y. S., Roe, J. H. (1995). "Isolation of a novel paraquat-inducible (pqi) gene regulated by the soxRS locus in Escherichia coli." J Bacteriol 177:2673-2678. Pubmed: 7751275
Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
Reddy, M., Gowrishankar, J. (1997). "Identification and characterization of ssb and uup mutants with increased frequency of precise excision of transposon Tn10 derivatives: nucleotide sequence of uup in Escherichia coli." J Bacteriol 179:2892-2899. Pubmed: 9139905