Putative N-acetylgalactosamine permease IIC component 2 (P42905)

Identification
Name:Putative N-acetylgalactosamine permease IIC component 2
Synonyms:
  • EIIC-Aga'
  • PTS system N-acetylgalactosamine-specific EIIC component 2
Gene Name:agaW
Enzyme Class:Not Available
Biological Properties
General Function:Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system
Specific Function:The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport
Cellular Location:Cell inner membrane; Multi-pass membrane protein.
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Transports:
Transport References:
  • Uniprot Consortium (2012). "Reorganizing the protein space at the Universal Protein Resource (UniProt)." Nucleic Acids Res 40:D71-D75. Pubmed: 22102590
Metabolites:
ECMDB IDNameView
ECMDB00853N-Acetyl-b-D-galactosamineMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Process
carbohydrate transport
establishment of localization
phosphoenolpyruvate-dependent sugar phosphotransferase system
transport
Gene Properties
Blattner:b3134
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>402 bp
ATGACGTTACCGAGTGGACACCCGAAGAGCAGATTGATCAAAAAATTTACCGCACTAGGC
CCGTATATTCGTGAAGGTAAGTGCAAAGATAATCGATTCTTTTTCGATTGTCTGGCTGTA
TGCGTCAACGTGAAACCGGCACCGGAAGTGCGTGAATTCTGGGGCTGGTGGATGGAGCTG
GAAGCGCAGGAATCCCGTTTTACCTACAGTTACCAGTTTGGTCTGTTCGATAAAGCAGGC
GACTGGAAGAGTGTTCCGGTAAAAGACACTGAAGTGGTTGAACGACTGGAGCACACCCTG
CGTGAGTTTCACGAGAAGCTGCGTGAACTGCTGACGACGCTGAATCTGAAGCTGGAACCG
GCGGATGATTTTCGTGACGAGCCGGTGAAGTTAACGGCGTGA
Protein Properties
Pfam Domain Function:
Protein Residues:133
Protein Molecular Weight:13721
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • 3-23
  • 33-53
  • 66-86
  • 94-114
Protein Sequence:
>Putative N-acetylgalactosamine permease IIC component 2
MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLGDLHTGILTGGTLELVW
MGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPFAVAVQMGITFLFSVMSGV
MSRCDLATNPRRI
References
External Links:
ResourceLink
Uniprot ID:P42905
Uniprot Name:PTPC2_ECOLI
GenBank Gene ID:U00096
Genebank Protein ID:1786435
ColiBase:b3134
Kegg Gene:b3134
EchoBASE ID:EB2618
CCDB:PTPC2_ECOLI
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
  • Reizer, J., Ramseier, T. M., Reizer, A., Charbit, A., Saier, M. H. Jr (1996). "Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli." Microbiology 142 ( Pt 2):231-250. Pubmed: 8932697