Identification
Name:Multidrug resistance protein MdtM
Synonyms:Not Available
Gene Name:mdtM
Enzyme Class:Not Available
Biological Properties
General Function:sodium ion transmembrane transport
Specific Function:Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
Transports:
Transport References:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
drug export
drug transmembrane transport
drug transmembrane transporter activity
drug:proton antiporter activity
integral component of membrane
plasma membrane
potassium ion transmembrane transport
potassium:proton antiporter activity
regulation of cellular pH
response to antibiotic
sodium ion transmembrane transport
sodium:proton antiporter activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1233
atgccacgtttttttacccgccatgccgccacgctgtttttcccgatggcgttgattttg
tatgactttgctgcgtatctgtcgacggatctgatccagcctgggatcattaatgtggta
cgtgattttaatgccgatgtcagtctggcccctgctgccgtcagtctctatcttgctggc
ggtatggcgttacagtggctgctggggccgctttccgacagaattggccgcaggccggtg
ctgattaccggggcgctaatttttacccttgcctgcgccgcgacaatgttcacaacgtct
atgacacagtttcttatcgcgcgtgcaattcagggcaccagtatctgttttattgccacc
gttggttatgtcacggtgcaggaggcgttcggacagacaaaagggatcaagttgatggcg
attatcacctccatcgtactgattgcgccgattatcggcccgctttccggcgcagctctg
atgcactttatgcactggaaagtcctttttgccatcattgcggttatgggttttatctca
tttgttggcttactgttggcgatgccagagacggtgaagcgcggcgcggttccgtttagc
gccaaaagcgtcttgcgcgattttcgtaatgtcttttgcaatcggctgttcctctttggc
gcagcaaccatctctttaagctatatcccgatgatgagctgggtggctgtctcgccggtg
atccttatcgatgcaggcagcttaacaacttcgcagttcgcctggacacaggttccggtg
ttcggcgcggtgattgttgcgaatgccatcgtggcgcgttttgttaaagatccgaccgaa
ccgcggtttatctggcgtgccgtacccattcaactggtcggcctctcgctgttgattgtc
ggcaatctgctgtcgccgcacgtctggctgtggtcggtgctgggcaccagtctgtatgct
ttcgggattggtttgattttcccgaccttattccgctttacgctgttttccaataagtta
ccgaaagggaccgtctccgcatcgctaaatatggtgatcctgatggtgatgtcggtctcg
gtcgaaatcggccgctggctatggtttaacggcggtcgcttgccgtttcatctgttagcc
gttgtggcgggcgttatcgtcgttttcaccctggcgggattgctcaatcgcgtgcgccag
catcaggcagccgagctagtggaggagcagtga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:410
Protein Molecular Weight:44687
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 12-32
  • 49-69
  • 79-99
  • 104-124
  • 141-161
  • 168-188
  • 217-237
  • 252-272
  • 283-303
  • 308-328
  • 349-369
  • 374-394
Protein Sequence:
>Multidrug resistance protein MdtM
MPRFFTRHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAG
GMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMTQFLIARAIQGTSICFIAT
VGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFMHWKVLFAIIAVMGFIS
FVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFLFGAATISLSYIPMMSWVAVSPV
ILIDAGSLTTSQFAWTQVPVFGAVIVANAIVARFVKDPTEPRFIWRAVPIQLVGLSLLIV
GNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFTLFSNKLPKGTVSASLNMVILMVMSVS
VEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLAGLLNRVRQHQAAELVEEQ
References
External Links:
ResourceLink
Uniprot ID:P39386
Uniprot Name:MDTM_ECOLI
CCDB:MDTM_ECOLI
General Reference:Not Available