Lysophospholipid transporter lplT (P39196)

• 2-acyl-glycero-3-phosphoethanolamine
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:1)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:1)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)
• 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:1)
• 2-Acyl-sn-glycero-3-phosphoglycerol (n-C12:0)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0)
• 2-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1)
• 2-dodecanoyl-sn-glycerol 3-phosphate
• 2-hexadec-9-enoyl-sn-glycerol 3-phosphate
• 2-hexadecanoyl-sn-glycerol 3-phosphate
• 2-octadec-11-enoyl-sn-glycerol 3-phosphate
• 2-octadecanoyl-sn-glycerol 3-phosphate
• 2-tetradec-7-enoyl-sn-glycerol 3-phosphate
• 2-tetradecanoyl-sn-glycerol 3-phosphate

• Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
• Uniprot Consortium (2012). "Reorganizing the protein space at the Universal Protein Resource (UniProt)." Nucleic Acids Res 40:D71-D75. Pubmed: 22102590

>1194 bp
ATGAGAGCCTGCATTAATAATCAACAGATTCGCCACCATAACAAATGCGTGATTCTGGAA
CTGCTGTACCGGCAAAAGCGCGCCAATAAATCAACGCTGGCCCGGCTGGCGCAAATTTCG
ATTCCGGCAGTCAGTAATATTTTGCAGGAACTGGAAAGCGAAAAACGGGTGGTGAATATT
GACGATGAAAGCCAGACGCGCGGGCATAGTAGCGGTACATGGCTGATTGCGCCGGAAGGT
GACTGGACGCTGTGCCTGAACGTGACGCCCACCAGTATTGAGTGTCAGGTTGCTAATGCT
TGTTTAAGTCCGAAAGGTGAATTTGAGTATTTACAGATTGATGCACCGACGCCGCAGGCG
CTGCTGTCCGAAATCGAAAAATGCTGGCATCGCCACCGTAAATTGTGGCCGGACCATACC
ATCAACCTGGCGTTGGCAATCCACGGTCAGGTTGATCCTGTGACCGGCGTGTCGCAAACC
ATGCCGCAAGCGCCGTGGACAACGCCGGTGGAGGTGAAATATCTGCTGGAAGAGAAGCTC
GGCATTCGGGTGATGGTCGATAATGACTGCGTGATGCTGGCGCTGGCGGAGAAATGGCAA
AATAATTCGCAGGAACGGGATTTCTGCGTGATCAACGTTGATTACGGCATTGGCTCGTCG
TTCGTGATTAACGAGCAAATTTATCGCGGCAGTTTGTATGGTAGCGGACAGATTGGTCAC
ACCATCGTTAATCCGGATGGCGTCGTCTGCGACTGTGGACGTTATGGCTGCCTGGAAACT
GTCGCCTCGTTAAGCGCATTAAAAAAACAGGCGCGGGTATGGCTAAAATCACAACCGGTT
AGTACTCAACTTGATCCTGAAAAACTGACTACAGCGCAGTTAATCGCTGCCTGGCAAAGT
GGAGAACCGTGGATCACCAGCTGGGTTGATCGCTCTGCCAATGCCATTGGTTTGAGTCTG
TATAACTTCCTCAACATCCTCAATATTAATCAGATTTGGTTGTACGGTCGCAGTTGTGCC
TTTGGTGAGAACTGGCTTAATACTATTATTCGCCAGACAGGATTTAACCCGTTCGACCGC
GACGAAGGACCGAGCGTGAAAGCGACGCAAATTGGCTTTGGGCAATTAAGCCGCGCACAA
CAGGTGCTGGGAATTGGCTATTTGTATGTTGAGGCGCAGTTACGACAGATTTGA

• MFS_1 (PF07690 )

• None

• 18-38
• 53-73
• 91-111
• 145-165
• 167-187
• 227-247
• 257-277
• 281-301
• 305-325
• 344-364
• 367-387

>Lysophospholipid transporter lplT
MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVG
AYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAK
YGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVA
NIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLV
LWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFS
LQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLG
IYSLAVMIGIPVVPIGIGFGALFALAITALWIWQRRH

• Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
• Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
• Harvat, E. M., Zhang, Y. M., Tran, C. V., Zhang, Z., Frank, M. W., Rock, C. O., Saier, M. H. Jr (2005). "Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily." J Biol Chem 280:12028-12034. Pubmed: 15661733
• Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
• Jackowski, S., Jackson, P. D., Rock, C. O. (1994). "Sequence and function of the aas gene in Escherichia coli." J Biol Chem 269:2921-2928. Pubmed: 8300626