| Identification |
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| Name: | Periplasmic pH-dependent serine endoprotease DegQ |
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| Synonyms: | Not Available |
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| Gene Name: | degQ |
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| Enzyme Class: | |
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| Biological Properties |
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| General Function: | proteolysis involved in cellular protein catabolic process |
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| Specific Function: | DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| identical protein binding | | integral component of external side of plasma membrane | | peptidase activity | | periplasmic space | | proteolysis | | proteolysis involved in cellular protein catabolic process | | serine-type endopeptidase activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1368
atgaaaaaacaaacccagctgttgagtgcattagcgttaagtgtcgggttaactctctcg
gcgtcatttcaggccgtcgcgtcgattccaggccaggttgccgatcaggcccctctcccc
agtctggctccaatgctggaaaaagtgcttccggcagtggtgagcgtacgggtggaagga
acggccagtcagggacagaaaatcccggaagaattcaaaaagttttttggtgatgattta
ccggatcaacctgcacaacccttcgaaggtttaggctccggtgtcatcatcaacgccagt
aaaggctatgtgctgaccaacaaccatgtgattaatcaggcacagaaaatcagtattcag
ctcaatgatgggcgcgagtttgatgcaaaactgattggtagcgatgaccagagcgatatc
gccctgttacaaattcaaaacccgagcaaattaacgcaaatcgctattgccgactccgat
aaattgcgcgtcggtgattttgccgtagcggtcggtaacccatttggccttgggcaaacc
gccacctctggcattgtttccgcattaggccgcagcgggttgaatcttgaaggtctggaa
aactttatccagacagatgcttccattaaccgcggtaactccggcggtgcactattaaac
cttaacggtgagttaattggcatcaacactgcaatccttgcgcctggcggcgggagcgtc
gggattggatttgccatccccagtaatatggcgcgaacactggcgcagcagcttatcgac
tttggtgaaatcaaacgcggtttgttaggcatcaaaggcaccgagatgagtgccgatatc
gccaaagccttcaaccttgacgtgcagcgtggcgcgtttgtcagcgaagtgttgccaggt
tctggctcggcaaaagcgggcgtcaaagcgggcgatattattaccagcctcaacggcaaa
ccgctgaatagctttgctgagttgcgctctcgtatcgcgaccaccgagccgggcacgaaa
gtgaagcttggcctgctgcgtaacggcaaaccactggaagtagaagtgacgctcgatacc
agcacctcttcgtcggccagcgctgaaatgatcacgccagcgctggaaggtgcaacgttg
agcgatggtcagctaaaagatggcggcaaaggtattaaaatcgatgaagttgtcaaagga
agcccagctgctcaggctggcttgcaaaaagacgatgtgatcattggcgtcaaccgcgat
cgggtgaactcgattgctgaaatgcgtaaagtgctggcggcaaaaccggccatcatcgcc
ctgcaaattgtacgcggcaatgaaagcatctatctgctgatgcgttaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 455 |
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| Protein Molecular Weight: | 47204 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 3STI |
| Signaling Regions: | |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Periplasmic pH-dependent serine endoprotease DegQ
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEG
TASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQ
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT
ATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPG
SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
STSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD
RVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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