Identification
Name:TorCAD operon transcriptional regulatory protein TorR
Synonyms:Not Available
Gene Name:torR
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Member of the two-component regulatory system TorS/TorR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Phosphorylated TorR activates the transcription of the torCAD operon by binding to four decameric boxes located in the torCAD promoter. Box1, 2 and 4 contain the DNA sequence 5'-CTGTTCATAT-3' and box3 contains the DNA sequence 5'-CCGTTCATCC-3'. Phosphorylated as well as unphosphorylated TorR negatively regulates its own expression by binding to box1 and 2.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA binding
phosphorelay response regulator activity
regulation of transcription, DNA-templated
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>693
atgccacatcacattgttattgttgaagatgagccggttacccaggcgcgattacaatcc
tacttcactcaggaggggtataccgtttccgttacggcgagcggtgctgggctacgggaa
attatgcagaatcagtcggtagatttaattctgctggatatcaacttacccgatgaaaat
ggcctgatgttaacccgcgccctgcgagaacgctcaacggtggggattattctggttacc
ggacgcagcgatcggattgaccgtattgttgggctggaaatgggcgcagacgattacgtc
accaaaccgctggaactgcgcgaactggtagtacgggtgaaaaatctgctctggcgaatc
gacctcgcgcgacaagctcaaccgcacactcaggacaactgctatcgctttgccggttat
tgcctgaatgtgtcgcgccatacgctggagcgggatggcgagccgattaaactgacccgc
gcagagtatgaaatgttggtggcatttgtgacgaatccgggcgaaattctcagccgtgaa
cgtctgctacgtatgctttctgcgcgtcgggtggaaaaccctgacctgcgcaccgtcgat
gtgttaattcgtcgtttacgtcataaactcagcgcggatttactggtgacgcaacatggt
gaaggttatttcttagccgctgatgtgtgctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:230
Protein Molecular Weight:26232
Protein Theoretical pI:Not Available
PDB File:1ZGZ
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>TorCAD operon transcriptional regulatory protein TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQSVDLILLDINLPDEN
GLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRI
DLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRE
RLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC
References
External Links:
ResourceLink
Uniprot ID:P38684
Uniprot Name:TORR_ECOLI
PDB ID:1ZGZ
CCDB:TORR_ECOLI
General Reference:Not Available