L-ribulose-5-phosphate 4-epimerase sgbE (P37680)

Identification
Name:L-ribulose-5-phosphate 4-epimerase sgbE
Synonyms:
  • Phosphoribulose isomerase
Gene Name:sgbE
Enzyme Class:
Biological Properties
General Function:Involved in metal ion binding
Specific Function:Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. May be involved in the utilization of 2,3- diketo-L-gulonate
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
  • Ascorbate and aldarate metabolism ec00053
  • Metabolic pathways eco01100
  • Microbial metabolism in diverse environments ec01120
  • Pentose and glucuronate interconversions ec00040
KEGG Reactions:
1.0Thumb ↔ 1.0Thumb
1.0L-Ribulose 5-phosphate ↔ 1.0Xylulose 5-phosphate
ReactionCard
EcoCyc Reactions:
1.0Thumb ↔ 1.0Thumb
1.0L-Ribulose 5-phosphate ↔ 1.0Xylulose 5-phosphate
ReactionCard
Complex Reactions:
1.0Thumb → 1.0Thumb
1.0L-Ribulose 5-phosphate → 1.0Xylulose 5-phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB24194 L-ribulose 5-phosphateMetaboCard
ECMDB20167L-Ribulose 5-phosphateMetaboCard
ECMDB04178Xylulose 5-phosphateMetaboCard
GO Classification:
Function
binding
catalytic activity
cation binding
ion binding
isomerase activity
L-ribulose-phosphate 4-epimerase activity
metal ion binding
racemase and epimerase activity
racemase and epimerase activity, acting on carbohydrates and derivatives
transition metal ion binding
zinc ion binding
Process
alcohol metabolic process
arabinose catabolic process
L-arabinose catabolic process
metabolic process
monosaccharide metabolic process
pentose catabolic process
pentose metabolic process
small molecule metabolic process
Gene Properties
Blattner:b3583
Gene OrientationClockwise
Centisome Percentage:80.78
Left Sequence End3748109
Right Sequence End3748804
Gene Sequence:
>696 bp
ATGGATAATCGAGGCGAATTTTTGAATAACGTTGCTCAGGCACTGGGTCGCCCGCTGCGA
CTTGAACCGCAAGCAGAAGATGCGCCGCTTAACAACTATGCTAACGAGCGGCTTACCCAA
CTTAACCAACAGCAGCGCTGTGACGCGTTTATTCAGTTTGCCAGCGATGTTATGTTGACG
CGCTGTGAGCTGACCAGCGAGGCGAAGGCGGCAGAAGCTGCAATACGTCTGTGTAAAGAG
CTGGGAGATCAGTCGGTCGTGATTAGCGGTGACACGAGGCTGGAGGAATTGGGGATTAGC
GAACGTTTGCAGCAGGAATGCAATGCCGTTGTTTGGGATCCGGCGAAAGGTGCCGAGAAT
ATCTCGCAGGCAGAGCAGGCTAAAGTGGGTGTTGTGTATGCTGAATATGGTTTAACCGAA
TCGGGAGGCGTGGTTCTTTTTTCCGCCGCCGAGCGCGGGCGTTCATTGAGCCTGCTCCCG
GAATATTCTCTTTTTATCCTGCGTAAAAGCACTATCCTGCCGCGTGTAGCGCAACTCGCA
GAAAAATTGCATCAGAAAGCGCAGGCCGGTGAACGAATGCCTTCCTGCATTAACATCATT
AGCGGCCCCAGTTCAACGGCGGATATTGAGCTTATCAAAGTCGTCGGAGTTCATGGCCCG
GTGAAAGCGGTGTATCTGATTATTGAGGATTGTTGA
Protein Properties
Pfam Domain Function:
Protein Residues:231
Protein Molecular Weight:25561
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>L-ribulose-5-phosphate 4-epimerase sgbE
MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPSGVEYDVMTADDMVVVE
IASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHATIWSQAGLDLPAWGTTHAD
YFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSPAQIPAVLVHSHGPFAWGKNA
ADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKHYLRKHGANAYYGQ
References
External Links:
ResourceLink
Uniprot ID:P37680
Uniprot Name:SGBE_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674452
Ecogene ID:EG12287
Ecocyc:EG12287
ColiBase:b3583
Kegg Gene:b3583
EchoBASE ID:EB2195
CCDB:SGBE_ECOLI
BacMap:16131454
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Ibanez, E., Gimenez, R., Pedraza, T., Baldoma, L., Aguilar, J., Badia, J. (2000). "Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose." J Bacteriol 182:4625-4627. Pubmed: 10913097
  • Sofia, H. J., Burland, V., Daniels, D. L., Plunkett, G. 3rd, Blattner, F. R. (1994). "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes." Nucleic Acids Res 22:2576-2586. Pubmed: 8041620
  • Yew, W. S., Gerlt, J. A. (2002). "Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons." J Bacteriol 184:302-306. Pubmed: 11741871