Endoglucanase (P37651)

Identification
Name:Endoglucanase
Synonyms:
  • Carboxymethylcellulase
  • CMCase
  • Cellulase
  • Endo-1,4-beta-glucanase
Gene Name:bcsZ
Enzyme Class:
Biological Properties
General Function:Involved in catalytic activity
Specific Function:Hydrolyzes carboxymethylcellulose
Cellular Location:Secreted
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Cellulose+1.0Thumb ↔ 1.0Cellulose+1.0Thumb
1.0Cellulose + 1.0Water ↔ 1.0Cellulose + 1.0Cellobiose
ReactionCard
1.01,4-beta-D-Glucan+1.0Thumb ↔ 1.01,4-beta-D-Glucan+1.0Cellobiose
1.01,4-beta-D-Glucan + 1.0Water ↔ 1.01,4-beta-D-Glucan + 1.0Cellobiose
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00055CellobioseMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing O-glycosyl compounds
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b3531
Gene OrientationCounterclockwise
Centisome Percentage:79.47
Left Sequence End3687178
Right Sequence End3688284
Gene Sequence:
>1107 bp
ATGCTCAGTCAAATTCAACGCTTTGGCGGCGCGATGTTCACGCCAGTGCTGCTGTTTCCC
TTCGCCGGGATTGTGGTGGGTCTTGCCATCTTGCTGCAAAACCCGATGTTTGTCGGGGAA
TCACTGACCGATCCGAACAGTTTATTCGCGCAAATCGTACACATTATTGAAGAGGGCGGT
TGGACGGTATTCCGTAATATGCCGCTGATTTTTGCTGTCGGTTTACCCATTGGCCTTGCT
AAGCAAGCGCAGGGGCGTGCTTGTCTGGCGGTGATGGTGAGTTTCCTGACCTGGAACTAT
TTCATCAACGCGATGGGAATGACCTGGGGAAGCTACTTCGGCGTCGATTTCACTCAGGAC
GCGGTGGCAGGTAGCGGTCTGACAATGATGGCCGGGATTAAAACCCTCGATACCAGCATT
ATCGGCGCAATTATCATTTCCGGCATTGTGACGGCGCTGCATAACCGTCTGTTCGATAAA
AAACTGCCGGTTTTTCTCGGCATTTTCCAGGGGACGTCTTATGTGGTGATTATCGCCTTC
CTGGTGATGATCCCCTGTGCCTGGCTGACGTTGCTCGGCTGGCCAAAAGTACAAATGGGG
ATTGAATCTCTGCAAGCGTTCCTGCGTTCGGCGGGTGCACTTGGGGTCTGGGTTTACACC
TTCCTCGAACGTATTCTGATCCCAACCGGTTTACACCACTTCATCTACGGACAGTTTATC
TTTGGTCCGGCAGCTGTTGAAGGCGGCATTCAGATGTACTGGGCGCAGCATCTGCAAGAG
TTCAGTTTGAGCGCCGAGCCGCTGAAATCGTTGTTCCCGGAAGGCGGTTTTGCCCTGCAC
GGTAACTCAAAAATCTTTGGTGCCGTGGGCATTTCTTTAGCGATGTACTTCACTGCCGCA
CCGGAAAATCGGGTAAAAGTGGCGGGCTTGCTGATTCCCGCAACCTTAACCGCCATGCTG
GTGGGAATTACCGAACCGCTGGAATTTACCTTCCTGTTCATTTCACCGTTGCTGTTTGCG
GTACACGCCGTGCTGGCGGCCTCAATGTCGACCGTAATGTATCTCTTTGGTGTGGTGGGC
AACATGGGCGGAGGTCTGATTGACTAG
Protein Properties
Pfam Domain Function:
Protein Residues:368
Protein Molecular Weight:41700
Protein Theoretical pI:9
Signaling Regions:
  • 1-21
Transmembrane Regions:
  • None
Protein Sequence:
>Endoglucanase
MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVIDPSDARKITTSEGQSYG
MFSALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKENSKWEVLDSNSASDGDVW
MAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLGSMLLPGKVGFAEDNSWRFNP
SYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFSPDWVRYEKDKGWQLKAEKTLIS
SYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTEKNGYPPEKVDVATGKAQGKGPVGF
SAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNYVLTLFGQGWDQHRFRFSTKGELLPDW
GQECANSH
References
External Links:
ResourceLink
Uniprot ID:P37651
Uniprot Name:GUN_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85676361
Ecogene ID:EG12258
Ecocyc:EG12258
ColiBase:b3531
Kegg Gene:b3531
EchoBASE ID:EB2167
CCDB:GUN_ECOLI
BacMap:16131403
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Park, Y. W., Yun, H. D. (1999). "Cloning of the Escherichia coli endo-1,4-D-glucanase gene and identification of its product." Mol Gen Genet 261:236-241. Pubmed: 10102357
  • Sofia, H. J., Burland, V., Daniels, D. L., Plunkett, G. 3rd, Blattner, F. R. (1994). "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes." Nucleic Acids Res 22:2576-2586. Pubmed: 8041620
  • Zogaj, X., Nimtz, M., Rohde, M., Bokranz, W., Romling, U. (2001). "The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix." Mol Microbiol 39:1452-1463. Pubmed: 11260463