Identification
Name:Multidrug resistance protein MdtE
Synonyms:Not Available
Gene Name:mdtE
Enzyme Class:Not Available
Biological Properties
General Function:transmembrane transport
Specific Function:Part of the tripartite efflux system MdtEF-TolC, which confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
plasma membrane
response to antibiotic
transmembrane transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1158
atgaacagaagaagaaagctgttaataccgttgttattctgcggcgcgatgctcaccgcc
tgcgatgacaaatcggcggaaaacgccgccgccatgacgcctgaggtcggtgtcgtcaca
ctctcccccggttcggtcaatgtgttgagcgaattgcccggtagaaccgttccttatgaa
gttgccgagatacgtccccaggtgggcggtattatcattaaacgcaactttatcgaaggc
gataaagtgaaccagggcgattcgctgtatcagattgatcctgcacctttacaggccgag
ctaaactccgccaaaggctcgctggcgaaagcgctctctaccgccagcaatgcccgcatc
acctttaaccgccaggcatcgttgctgaagaccaactacgttagccgtcaggattacgac
accgcgcgcacccagttgaatgaagcagaagccaatgtcaccgtcgccaaagcggctgtt
gaacaggcgacgatcaatctgcaatacgcgaatgtcacctcgccgattacgggcgtcagc
gggaaatcgtcggtgaccgtcggcgcactcgttaccgctaatcaggcagattcgctggtt
accgtacaacgtctggacccgatttatgtcgatctcacgcagtcggtgcaagatttctta
cgcatgaaagaagaggtcgccagtgggcaaatcaaacaggttcagggcagtacgccagta
cagctcaatctggaaaatggtaaacgctacagccagaccggcacgctgaaattctccgac
ccgacagtggatgaaaccacgggctccgtgacgttacgggcgattttccccaacccaaat
ggtgacttgctgcctggcatgtacgtcacggcattagtggatgaaggtagccgccagaat
gtattactggtgccgcaggaaggcgtcacccacaacgcccagggtaaagcaacggcgctc
attctggataaagacgatgtcgtgcagctacgcgaaattgaagccagcaaagccatcggc
gaccagtgggtcgtcacctctggcttgcaggctggcgatcgggtgatcgtttccggtttg
caacgcattcgtccgggtatcaaagcacgagcaatttcctccagccaggaaaacgccagc
accgaatcgaaacaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:385
Protein Molecular Weight:41190
Protein Theoretical pI:Not Available
Signaling Regions:
  • 1-20
Transmembrane Regions:Not Available
Protein Sequence:
>Multidrug resistance protein MdtE
MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPGSVNVLSELPGRTVPYE
VAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARI
TFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPITGVS
GKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQDFLRMKEEVASGQIKQVQGSTPV
QLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTALVDEGSRQN
VLLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGL
QRIRPGIKARAISSSQENASTESKQ
References
External Links:
ResourceLink
Uniprot ID:P37636
Uniprot Name:MDTE_ECOLI
CCDB:MDTE_ECOLI
General Reference:Not Available