Identification
Name:Ribosomal RNA large subunit methyltransferase J
Synonyms:Not Available
Gene Name:rlmJ
Enzyme Class:
Biological Properties
General Function:rRNA base methylation
Specific Function:Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
23S rRNA (adenine(2030)-N(6))-methyltransferase activity
carbon utilization
RNA binding
rRNA (adenine-N6-)-methyltransferase activity
rRNA base methylation
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>843
atgctcagttatcgccacagctttcacgctggcaaccacgccgacgtccttaaacatacc
gttcagagcctgatcatcgagtcgctgaaagagaaagataaaccgtttctctatctcgac
acccacgcaggggccgggcgttatcagttaggcagcgaacatgccgagcgtaccggcgaa
tatctcgaaggcatcgcccgtatctggcagcaggacgatttgcccgcagaactggaggcg
tacatcaatgtggtaaaacacttcaaccgtagcggtcagttgcgttactaccccggttcg
ccgttgattgctcgcctgctactgcgtgaacaggacagcctgcaactgaccgaactgcac
ccgagcgattacccgttgttgcgttctgaatttcagaaagatagccgtgcgcgtgtcgaa
aaagccgacggtttccagcagcttaaggccaaactgccgccggtttcccgccgtggttta
atccttatcgacccgccgtatgaaatgaaaactgactatcaagcggtggtcagcgggata
gcagaaggttacaaacgtttcgccactggtatttacgcactgtggtatccggtggtgctg
cgtcagcaaattaagcgcatgatccacgatctggaagcgaccggtattcgcaaaattctg
caaattgaactggcggtactgccagacagcgatcgccgtggcatgaccgcttccggcatg
attgtgattaacccgccgtggaaactggaacaacagatgaataacgtgctgccgtggctg
cacagcaaactggttccggcaggcaccgggcacgccaccgtaagctggatcgtgccggag
taa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:280
Protein Molecular Weight:31941
Protein Theoretical pI:Not Available
PDB File:4BLU
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Ribosomal RNA large subunit methyltransferase J
MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLGSEHAERTGE
YLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIARLLLREQDSLQLTELH
PSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGLILIDPPYEMKTDYQAVVSGI
AEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRKILQIELAVLPDSDRRGMTASGM
IVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSWIVPE
References
External Links:
ResourceLink
Uniprot ID:P37634
Uniprot Name:RLMJ_ECOLI
PDB ID:4BLU
CCDB:RLMJ_ECOLI
General Reference:Not Available