ECMDB

Identification

Name:

Putative cyclic-di-GMP phosphodiesterase YjcC

Synonyms:

Not Available

Gene Name:

yjcC

Enzyme Class:

3.1.4.52

Biological Properties

General Function:

cyclic-guanylate-specific phosphodiesterase activity

Specific Function:

May function as a c-di-GMP phosphodiesterase. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Overexpression reduces biofilm formation.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

KEGG Reactions:

1.03',5'-Cyclic diGMP

1.0

↔

1.0

1.03',5'-Cyclic diGMP + 1.0Water + 1.0Cyclic di-3',5'-guanylate ↔ 1.0Linear dimeric GMP
ReactionCard

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cyclic-guanylate-specific phosphodiesterase activity
integral component of membrane
plasma membrane

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>1587
atgagtcatcgtgcacgacaccaattactggcgttgccgggcattatctttttagttctc
tttcccatcattctttcgctatggattgccttcctttgggcaaaatcagaagtgaataat
cagctccgaacctttgctcaactggcactggataaatccgagctggtcattcgccaggca
gatttagtgagcgatgcagctgaacgctatcaggggcaagtttgcactccagcccatcaa
aagcgaatgttgaatattattcgtggctatctttatattaatgaattgatctatgcccgt
gataaccattttttatgctcatcgctgatagcgcctgtaaacggctatacgattgcaccg
gccgattataagcgtgaacctaacgtttctatctattattaccgcgatacgccttttttc
tctggctataaaatgacctatatgcagcggggaaattatgtggcggttatcaaccctctc
ttctggagtgaagtgatgtctgatgacccgacattgcaatggggtgtgtatgatacggtg
acgaaaacctttttctcgttaagcaaagaggcctcggcagcaacgttttctccgctgatt
catttgaaggatttaaccgtacaaagaaatggctatttatatgcgacagtttattcgaca
aaacgcccaattgcagccattgttgcgacttcatatcaacgtcttataacccatttttat
aatcatcttatttttgcgttgcccgccggtattttggggagtcttgttctgctattactc
tggctacgtattcgacaaaactatttatctcccaaacgtaaattgcaacgcgccctcgaa
aaacatcaactttgtctttattaccagccaataatcgatatcaaaacagaaaaatgtatc
ggcgctgaagcgttgttacgttggcctggtgagcaggggcaaataatgaatccggcagag
tttattccgctggcagaaaaggaggggatgatagaacagataactgattatgttattgat
aatgtcttccgcgatctgggcgattacctggcaacacatgcagatcgctatgtttctatt
aacctgtcggcctccgattttcatacgtcacggttgatagcgcgaatcaatcagaaaaca
gagcaatacgcggtgcgtccgcagcaaattaaatttgaagtgactgagcatgcatttctt
gatgttgacaaaatgacgccgattattctggctttccgccaggcaggttacgaagtggca
attgatgattttggtattggctactctaacttgcataaccttaaatcattgaatgtcgat
attttgaaaatcgacaaatcgtttgttgaaacgctgaccacccacaaaaccagtcatttg
attgcggaacacatcatcgagctggcgcacagcctggggttaaaaacgatcgctgaaggc
gtcgaaactgaggagcaggttaactggctgcgcaaacgcggcgtgcgctattgccaggga
tggttctttgcgaaggcgatgccgccgcaggtgtttatgcaatggatggagcaattaccc
gcgcgggagttaacgcgcgggcaataa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

528

Protein Molecular Weight:

60800

Protein Theoretical pI:

Not Available

Signaling Regions:

Not Available

Transmembrane Regions:

14-34
242-262

Protein Sequence:

>Putative cyclic-di-GMP phosphodiesterase YjcC
MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRTFAQLALDKSELVIRQA
DLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAP
ADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTV
TKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCI
GAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQITDYVIDNVFRDLGDYLATHADRYVSI
NLSASDFHTSRLIARINQKTEQYAVRPQQIKFEVTEHAFLDVDKMTPIILAFRQAGYEVA
IDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

References

External Links:

Resource	Link
Uniprot ID:	P32701
Uniprot Name:	YJCC_ECOLI
CCDB:	YJCC_ECOLI

General Reference:

Not Available

Putative cyclic-di-GMP phosphodiesterase YjcC (P32701)