Identification
Name:Multidrug resistance protein MdtL
Synonyms:Not Available
Gene Name:mdtL
Enzyme Class:Not Available
Biological Properties
General Function:response to antibiotic
Specific Function:Confers resistance to chloramphenicol.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
drug transmembrane transport
integral component of membrane
plasma membrane
response to antibiotic
transporter activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1176
atgtcccgctttttgatttgtagttttgccctggttttactttatcccgccgggattgat
atgtacctcgttggtttaccgcgcatcgccgccgatctcaatgccagcgaagcgcagttg
catattgcgttctccgtatatctggcggggatggcagctgcgatgttatttgccggtaaa
gtggccgatcgttcagggagaaagccggtcgccatacccggcgcggcgctatttattatt
gcctcggtgttctgttcactggctgaaaccagcacgttatttcttgcaggccgatttcta
caggggttgggcgcaggctgttgttacgtagtggcgttcgctattttgcgcgacacgctg
gatgatcgacgtcgggctaaagtgctgtcattactcaacggtattacctgcatcattccg
gtgttagcgccagtgctcggacatctgattatgcttaaattcccgtggcagagtctgttc
tgggcgatggcaatgatgggcatcgcggtactgatgttgtctttgtttattttaaaagaa
acgcgcccagcggcccccgcagcttcggataaaccacgagaaaatagcgagtcgctgctt
aaccgttttttcctcagccgtgttgttatcaccaccctcagcgtttcggtgatcctcact
ttcgtcaacacgtcaccggtattgctgatggaaatcatggggtttgagcgcggtgaatac
gccaccattatggcgctgaccgctggcgtcagcatgaccgtttcattctccacgccattt
gcgctgggaatttttaagccacgtacgttgatgatcacctcgcaggtgttattcctggcg
gcggggatcactcttgccgtttcaccttcccatgcggtttctctgtttggtatcacgctg
atttgcgccggtttctcggtaggttttggtgtggcgatgagtcaggcgttagggccgttt
tcattacgcgcgggcgtagccagctcgaccttaggtattgcgcaggtttgcggttcgtca
ctgtggatttggctggcagcggtggttggtatcggcgcatggaatatgctgatcgggatt
ctgattgcctgtagcatagtgagcctgttgctgattatgttcgtcgcgcctggacgcccc
gttgccgctcatgaagaaatccatcaccacgcttga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:391
Protein Molecular Weight:41489
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 4-24
  • 42-62
  • 69-89
  • 93-113
  • 131-151
  • 158-178
  • 203-222
  • 245-265
  • 269-289
  • 293-313
  • 331-351
  • 356-376
Protein Sequence:
>Multidrug resistance protein MdtL
MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGK
VADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTL
DDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMAMMGIAVLMLSLFILKE
TRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEY
ATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITL
ICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGI
LIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
References
External Links:
ResourceLink
Uniprot ID:P31462
Uniprot Name:MDTL_ECOLI
CCDB:MDTL_ECOLI
General Reference:Not Available