| Identification |
|---|
| Name: | Tat-linked quality control protein TatD |
|---|
| Synonyms: | Not Available |
|---|
| Gene Name: | tatD |
|---|
| Enzyme Class: | Not Available |
|---|
| Biological Properties |
|---|
| General Function: | misfolded or incompletely synthesized protein catabolic process |
|---|
| Specific Function: | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Although TatD is not required for export activity, it is a central component of a quality control system that is linked to the Tat translocation system. May act by degrading wild-type pre-protein molecules that are misfolded. Shows magnesium-dependent DNase activity. |
|---|
| Cellular Location: | Not Available |
|---|
| SMPDB Pathways: | Not Available |
|---|
| KEGG Pathways: | Not Available |
|---|
| Metabolites: | |
|---|
| GO Classification: | | Function |
|---|
| cytoplasm | | deoxyribonuclease activity | | DNA catabolic process | | endodeoxyribonuclease activity, producing 5'-phosphomonoesters | | metal ion binding | | misfolded or incompletely synthesized protein catabolic process |
|
|---|
| Gene Properties |
|---|
| Blattner: | Not Available |
|---|
| Gene Orientation | Not Available |
|---|
| Centisome Percentage: | Not Available |
|---|
| Left Sequence End | Not Available |
|---|
| Right Sequence End | Not Available |
|---|
| Gene Sequence: | >783
atgtttgatatcggcgttaatttgaccagttcgcaatttgcgaaagaccgtgatgatgtt
gtagcgtgcgcttttgacgcgggagttaatgggctactcatcaccggcactaacctgcgt
gaaagccagcaggcgcaaaagctggcgcgtcagtattcgtcctgttggtcaacggcgggc
gtacatcctcacgacagcagccagtggcaagctgcgactgaagaagcgattattgagctg
gccgcgcagccagaagtggtggcgattggtgaatgtggtctcgactttaaccgcaacttt
tcgacgccggaagagcaggaacgcgcttttgttgcccagctacgcattgccgcagattta
aacatgccggtatttatgcactgtcgcgatgcccacgagcggtttatgacattgctggag
ccgtggctggataaactgcctggtgcggttcttcattgctttaccggcacacgcgaagag
atgcaggcgtgcgtggcgcatggaatttatatcggcattaccggttgggtttgcgatgaa
cgacgcggactggagctgcgggaacttttgccgttgattccggcggaaaaattactgatc
gaaactgatgcgccgtatctgctccctcgcgatctcacgccaaagccatcatcccggcgc
aacgagccagcccatctgccccatattttgcaacgtattgcgcactggcgtggagaagat
gccgcatggctggctgccaccacggatgctaatgtcaaaacactgtttgggattgcgttt
tag |
|---|
| Protein Properties |
|---|
| Pfam Domain Function: | Not Available |
|---|
| Protein Residues: | 260 |
|---|
| Protein Molecular Weight: | 28973 |
|---|
| Protein Theoretical pI: | Not Available |
|---|
| PDB File: | 1XWY |
| Signaling Regions: | Not Available |
|---|
| Transmembrane Regions: | Not Available |
|---|
| Protein Sequence: | >Tat-linked quality control protein TatD
MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAG
VHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFSTPEEQERAFVAQLRIAADL
NMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVAHGIYIGITGWVCDE
RRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGED
AAWLAATTDANVKTLFGIAF |
|---|
| References |
|---|
| External Links: | |
|---|
| General Reference: | Not Available |
|---|
