[Protein-PII] uridylyltransferase (P27249)

Identification
Name:[Protein-PII] uridylyltransferase
Synonyms:
  • PII uridylyl-transferase
  • UTase
  • Uridylyl-removing enzyme
Gene Name:glnD
Enzyme Class:
Biological Properties
General Function:Involved in amino acid binding
Specific Function:Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0[Protein-PII] ↔ 1.0Thumb+1.0Uridylyl-[protein-PII]
1.0Uridine triphosphate + 1.0[Protein-PII] ↔ 1.0Pyrophosphate + 1.0Uridylyl-[protein-PII]
ReactionCard
Complex Reactions:
1.0Thumb+1.0[protein-PII] → 1.0Thumb+1.0uridylyl-[protein-PII]
1.0Uridine triphosphate + 1.0[protein-PII] → 1.0Pyrophosphate + 1.0uridylyl-[protein-PII]
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB04142PyrophosphateMetaboCard
ECMDB00285Uridine triphosphateMetaboCard
GO Classification:
Function
amino acid binding
binding
carboxylic acid binding
catalytic activity
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
uridylyltransferase activity
[protein-PII] uridylyltransferase activity
Process
metabolic process
nitrogen compound metabolic process
Gene Properties
Blattner:b0167
Gene OrientationCounterclockwise
Centisome Percentage:4.01
Left Sequence End185978
Right Sequence End188650
Gene Sequence:
>2673 bp
ATGAATACCCTTCCAGAACAGTACGCAAACACCGCTCTCCCCACCCTGCCCGGTCAACCG
CAAAATCCATGCGTCTGGCCCCGTGATGAATTAACCGTCGGTGGGATAAAAGCCCATATC
GATACTTTCCAGCGTTGGCTGGGTGATGCCTTTGACAATGGGATCTCTGCAGAACAGTTG
ATTGAGGCGCGCACCGAGTTTATCGACCAGCTCCTGCAACGATTATGGATTGAAGCGGGA
TTCAGCCAGATTGCCGACCTGGCATTGGTCGCCGTCGGTGGCTACGGTCGTGGCGAGCTG
CATCCACTTTCAGACGTCGATTTACTGATTTTAAGCCGTAAAAAGCTCCCGGACGATCAG
GCGCAAAAAGTGGGCGAGCTGTTAACGCTGCTCTGGGATGTAAAGCTGGAAGTCGGTCAT
AGCGTGCGCACGCTTGAAGAGTGCATGCTGGAAGGGTTATCGGATTTAACCGTCGCCACC
AATTTAATCGAATCCCGCTTATTAATTGGCGATGTTGCGCTGTTCCTCGAACTGCAAAAA
CATATTTTCAGCGAAGGATTCTGGCCTTCCGACAAGTTCTACGCGGCGAAAGTTGAAGAA
CAGAACCAGCGCCATCAGCGTTACCATGGCACCAGCTACAACCTTGAACCAGACATCAAA
AGCAGCCCTGGCGGCTTGCGCGATATCCACACTCTGCAATGGGTGGCCCGCCGTCATTTT
GGCGCAACATCGCTGGATGAAATGGTCGGGTTTGGCTTCTTAACCTCAGCGGAGCGGGCG
GAATTAAACGAATGTCTGCATATATTGTGGCGTATTCGCTTTGCCCTGCATCTGGTCGTC
AGCCGTTACGATAATCGCCTGTTATTCGATCGCCAGCTTAGCGTCGCCCAGCGTCTGAAT
TACAGTGGTGAAGGTAACGAACCGGTCGAGCGGATGATGAAGGATTACTTCCGCGTTACA
CGCCGCGTCAGTGAACTCAACCAGATGCTGCTGCAACTGTTCGATGAAGCCATCCTCGCC
CTTCCCGCCGACGAAAAACCACGTCCAATCGACGATGAGTTTCAGCTACGCGGTACGCTA
ATCGACCTGCGTGATGAAACACTATTTATGCGCCAGCCGGAAGCCATCTTGCGTATGTTC
TACACCATGGTGCACAACAGTGCGATCACCGGCATTTACTCCACCACGCTGCGCCAGTTA
CGCCATGCCCGTCGCCATCTGCAACAACCGCTGTGTAATATTCCGGAAGCACGAAAACTG
TTTTTGAGCATTCTGCGTCACCCCGGAGCGGTGCGGCGCGGGCTATTGCCAATGCATCGC
CATAGCGTGCTCGGCGCGTATATGCCGCAATGGTCGCATATCGTCGGGCAGATGCAGTTT
GATCTGTTCCACGCCTACACGGTGGATGAACATACTATCCGCGTGATGCTGAAACTGGAG
AGTTTTGCCAGTGAAGAAACGCGCCAGCGCCATCCGTTGTGTGTGGACGTCTGGCCGCGC
CTGCCGTCAACTGAGCTGATTTTCATCGCCGCGCTGTTTCACGATATCGCCAAAGGACGC
GGCGGCGACCACTCCATTCTCGGTGCTCAGGATGTAGTGCATTTTGCCGAACTCCACGGG
CTGAACTCACGCGAAACACAGCTGGTCGCCTGGCTGGTTCGCCAGCACCTGTTGATGTCG
GTGACCGCCCAACGCCGCGATATTCAGGACCCGGAAGTCATCAAGCAGTTTGCCGAAGAA
GTGCAAACGGAAAATCGTCTGCGCTATCTGGTATGCCTGACTGTGGCTGACATTTGCGCC
ACCAACGAAACGCTGTGGAATAGCTGGAAGCAAAGTCTGTTGCGTGAGCTCTACTTTGCC
ACCGAAAAGCAGCTACGACGCGGAATGCAAAACACGCCGGATATGCGCGAACGGGTTCGC
CATCACCAACTCCAGGCACTGGCACTACTGCGCATGGATAACATCGACGAAGAGGCGCTG
CACCAAATTTGGTCACGCTGTCGTGCTAACTATTTTGTCCGCCATAGCCCAAATCAACTG
GCCTGGCATGCCCGCCATTTATTACAGCATGATTTAAGCAAACCGCTGGTATTGCTTAGC
CCGCAGGCTACGCGTGGAGGCACCGAGATTTTTATCTGGAGCCCGGACCGCCCTTATCTG
TTTGCCGCCGTCTGTGCCGAATTAGACCGCCGCAATTTAAGTGTTCACGACGCACAAATT
TTCACCACTCGCGACGGTATGGCGATGGATACCTTTATCGTGCTGGAACCCGATGGCAAC
CCGCTGTCCGCAGATCGTCATGAGGTTATTCGGTTTGGTCTGGAGCAAGTACTGACGCAA
AGTAGCTGGCAGCCACCGCAGCCCCGTCGCCAACCCGCCAAATTACGCCATTTTACTGTT
GAAACCGAAGTAACGTTTTTGCCGACCCATACCGACCGCAAATCGTTCCTCGAACTGATC
GCCCTCGACCAACCTGGACTGCTGGCGCGAGTCGGGAAAATTTTTGCCGATCTGGGAATT
TCGCTTCATGGTGCCCGAATTACAACCATTGGCGAGCGAGTAGAAGATTTATTCATAATT
GCCACCGCTGACCGGCGTGCGCTTAATAACGAGTTGCAGCAGGAAGTGCATCAGCGGTTG
ACAGAGGCCCTCAATCCAAACGATAAAGGGTGA
Protein Properties
Pfam Domain Function:
Protein Residues:890
Protein Molecular Weight:102389
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>[Protein-PII] uridylyltransferase
MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQL
IEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDVDLLILSRKKLPDDQ
AQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQK
HIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHF
GATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLN
YSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTL
IDLRDETLFMRQPEAILRMFYTMVHNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKL
FLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLE
SFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHG
LNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICA
TNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEAL
HQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYL
FAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQ
SSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGI
SLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
References
External Links:
ResourceLink
Uniprot ID:P27249
Uniprot Name:GLND_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674365
Ecogene ID:EG11411
Ecocyc:EG11411
ColiBase:b0167
Kegg Gene:b0167
EchoBASE ID:EB1383
CCDB:GLND_ECOLI
BacMap:16128160
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Fujita, N., Mori, H., Yura, T., Ishihama, A. (1994). "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region." Nucleic Acids Res 22:1637-1639. Pubmed: 8202364
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • van Heeswijk, W. C., Rabenberg, M., Westerhoff, H. V., Kahn, D. (1993). "The genes of the glutamine synthetase adenylylation cascade are not regulated by nitrogen in Escherichia coli." Mol Microbiol 9:443-457. Pubmed: 8412694