ECMDB

Identification

Name:

Multiple antibiotic resistance protein MarR

Synonyms:

Not Available

Gene Name:

marR

Enzyme Class:

Not Available

Biological Properties

General Function:

transcription, DNA-templated

Specific Function:

Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.

Cellular Location:

Not Available

SMPDB Pathways:

Collection of Reactions without pathways PW001891

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cellular response to antibiotic
DNA binding
negative regulation of transcription, DNA-templated
response to heat
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>435
gtgaaaagtaccagcgatctgttcaatgaaattattccattgggtcgcttaatccatatg
gttaatcagaagaaagatcgcctgcttaacgagtatctgtctccgctggatattaccgcg
gcacagtttaaggtgctctgctctatccgctgcgcggcgtgtattactccggttgaactg
aaaaaggtattgtcggtcgacctgggagcactgacccgtatgctggatcgcctggtctgt
aaaggctgggtggaaaggttgccgaacccgaatgacaagcgcggcgtactggtaaaactt
accaccggcggcgcggcaatatgtgaacaatgccatcaattagttggccaggacctgcac
caagaattaacaaaaaacctgacggcggacgaagtggcaacacttgagtatttgcttaag
aaagtcctgccgtaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

144

Protein Molecular Weight:

16064

Protein Theoretical pI:

Not Available

PDB File:

1JGS

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Multiple antibiotic resistance protein MarR
MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVEL
KKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLH
QELTKNLTADEVATLEYLLKKVLP

References

External Links:

Resource	Link
Uniprot ID:	P27245
Uniprot Name:	MARR_ECOLI
PDB ID:	1JGS
CCDB:	MARR_ECOLI

General Reference:

Not Available

Multiple antibiotic resistance protein MarR (P27245)