Identification
Name:Tellurite methyltransferase
Synonyms:Not Available
Gene Name:tehB
Enzyme Class:
Biological Properties
General Function:response to tellurium ion
Specific Function:S-adenosyl-L-methionine dependent methyltransferase that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Can not methylate arsenic compounds.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
response to antibiotic
response to tellurium ion
S-adenosylmethionine-dependent methyltransferase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>594
atgatcattcgtgacgaaaactattttactgataaatatgaattaacccgcacacactct
gaagtactggaagcggtgaaagtggttaaaccgggtaaaacgctggatctgggctgtggc
aatggtcgtaacagtctttacctggcagccaatggttatgatgttgacgcatgggataaa
aatgccatgagtatcgccaacgtcgagcgcattaaatccattgaaaatctggataattta
cacacccgagtcgttgatctgaataacctcacatttgatagacagtacgattttattctt
tcgactgtggtgctgatgttccttgaggctaaaaccatccccgggttgattgccaatatg
caacgttgcactaaacctggtggttacaacctgattgtggcggcgatggataccgctgat
tatccatgtaccgtcggcttcccgtttgccttcaaagagggagaattacgtcgatattac
gaaggctgggagagggtgaaatacaatgaagacgtcggcgagctgcaccgcaccgacgcc
aacggtaatcgtattaaactgcgtttcgccacgatgctggcacgtaaaaaatga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:197
Protein Molecular Weight:22530
Protein Theoretical pI:Not Available
PDB File:2XVA
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Tellurite methyltransferase
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILSTVVLMFLEAKTIPGLIANM
QRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYYEGWERVKYNEDVGELHRTDA
NGNRIKLRFATMLARKK
References
External Links:
ResourceLink
Uniprot ID:P25397
Uniprot Name:TEHB_ECOLI
PDB ID:2XVA
CCDB:TEHB_ECOLI
General Reference:Not Available