Identification |
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Name: | DNA mismatch repair protein MutS |
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Synonyms: | Not Available |
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Gene Name: | mutS |
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Enzyme Class: | Not Available |
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Biological Properties |
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General Function: | regulation of DNA recombination |
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Specific Function: | This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. |
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Cellular Location: | Not Available |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | |
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Metabolites: | |
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GO Classification: | Function |
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adenine/cytosine mispair binding | ADP binding | ATP binding | ATPase activity | cellular response to DNA damage stimulus | cytosol | damaged DNA binding | DNA binding, bending | DNA-dependent ATPase activity | identical protein binding | mismatch repair | mismatch repair complex | mismatched DNA binding | regulation of DNA recombination |
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Gene Properties |
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Blattner: | Not Available |
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Gene Orientation | Not Available |
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Centisome Percentage: | Not Available |
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Left Sequence End | Not Available |
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Right Sequence End | Not Available |
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Gene Sequence: | >2562
atgagtgcaatagaaaatttcgacgcccatacgcccatgatgcagcagtatctcaggctg
aaagcccagcatcccgagatcctgctgttttaccggatgggtgatttttatgaactgttt
tatgacgacgcaaaacgcgcgtcgcaactgctggatatttcactgaccaaacgcggtgct
tcggcgggagagccgatcccgatggcggggattccctaccatgcggtggaaaactatctc
gccaaactggtgaatcagggagagtccgttgccatctgcgaacaaattggcgatccggcg
accagcaaaggtccggttgagcgcaaagttgtgcgtatcgttacgccaggcaccatcagc
gatgaagccctgttgcaggagcgtcaggacaacctgctggcggctatctggcaggacagc
aaaggtttcggctacgcgacgctggatatcagttccgggcgttttcgcctgagcgaaccg
gctgaccgcgaaacgatggcggcagaactgcaacgcactaatcctgcggaactgctgtat
gcagaagattttgctgaaatgtcgttaattgaaggccgtcgcggcctgcgccgtcgcccg
ctgtgggagtttgaaatcgacaccgcgcgccagcagttgaatctgcaatttgggacccgc
gatctggtcggttttggcgtcgagaacgcgccgcgcggactttgtgctgccggttgtctg
ttgcagtatgcgaaagatacccaacgtacgactctgccgcatattcgttccatcaccatg
gaacgtgagcaggacagcatcattatggatgccgcgacgcgtcgtaatctggaaatcacc
cagaacctggcgggtggtgcggaaaatacgctggcttctgtgctcgactgcaccgtcacg
ccgatgggcagccgtatgctgaaacgctggctgcatatgccagtgcgcgatacccgcgtg
ttgcttgagcgccagcaaactattggcgcattgcaggatttcaccgccgggctacagccg
gtactgcgtcaggtcggcgacctggaacgtattctggcacgtctggctttacgaactgct
cgcccacgcgatctggcccgtatgcgccacgctttccagcaactgccggagctgcgtgcg
cagttagaaactgtcgatagtgcaccggtacaggcgctacgtgagaagatgggcgagttt
gccgagctgcgcgatctgctggagcgagcaatcatcgacacaccgccggtgctggtacgc
gacggtggtgttatcgcatcgggctataacgaagagctggatgagtggcgcgcgctggct
gacggcgcgaccgattatctggagcgtctggaagtccgcgagcgtgaacgtaccggcctg
gacacgctgaaagttggctttaatgcggtgcacggctactacattcaaatcagccgtggg
caaagccatctggcacccatcaactacatgcgtcgccagacgctgaaaaacgccgagcgc
tacatcattccagagctaaaagagtacgaagataaagttctcacctcaaaaggcaaagca
ctggcactggaaaaacagctttatgaagagctgttcgacctgctgttgccgcatctggaa
gcgttgcaacagagcgcgagcgcgctggcggaactcgacgtgctggttaacctggcggaa
cgggcctataccctgaactacacctgcccgaccttcattgataaaccgggcattcgcatt
accgaaggtcgccatccggtagttgaacaagtactgaatgagccatttatcgccaacccg
ctgaatctgtcgccgcagcgccgcatgttgatcatcaccggtccgaacatgggcggtaaa
agtacctatatgcgccagaccgcactgattgcgctgatggcctacatcggcagctatgta
ccggcacaaaaagtcgagattggacctatcgatcgcatctttacccgcgtaggcgcggca
gatgacctggcgtccgggcgctcaacctttatggtggagatgactgaaaccgccaatatt
ttacataacgccaccgaatacagtctggtgttaatggatgagatcgggcgtggaacgtcc
acctacgatggtctgtcgctggcgtgggcgtgcgcggaaaatctggcgaataagattaag
gcattgacgttatttgctacccactatttcgagctgacccagttaccggagaaaatggaa
ggcgtcgctaacgtgcatctcgatgcactggagcacggcgacaccattgcctttatgcac
agcgtgcaggatggcgcggcgagcaaaagctacggcctggcggttgcagctctggcaggc
gtgccaaaagaggttattaagcgcgcacggcaaaagctgcgtgagctggaaagcatttcg
ccgaacgccgccgctacgcaagtggatggtacgcaaatgtctttgctgtcagtaccagaa
gaaacttcgcctgcggtcgaagctctggaaaatcttgatccggattcactcaccccgcgt
caggcgctggagtggatttatcgcttgaagagcctggtgtaa |
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Protein Properties |
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Pfam Domain Function: | Not Available |
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Protein Residues: | 853 |
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Protein Molecular Weight: | 95245 |
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Protein Theoretical pI: | Not Available |
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PDB File: | 1E3M |
Signaling Regions: | Not Available |
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Transmembrane Regions: | Not Available |
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Protein Sequence: | >DNA mismatch repair protein MutS
MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGA
SAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTIS
DEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLY
AEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCL
LQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVT
PMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTA
RPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVR
DGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRG
QSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLE
ALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANP
LNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAA
DDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIK
ALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAG
VPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPR
QALEWIYRLKSLV |
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References |
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External Links: | |
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General Reference: | Not Available |
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