Identification
Name:Tail-specific protease
Synonyms:Not Available
Gene Name:prc
Enzyme Class:
Biological Properties
General Function:response to drug
Specific Function:Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
endopeptidase activity
outer membrane-bounded periplasmic space
plasma membrane
protein catabolic process
proteolysis
response to drug
serine-type peptidase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>2049
atgaacatgttttttaggcttaccgcgttagctggcctgcttgcaatagcaggccagacc
ttcgctgtagaagatatcacgcgtgctgatcaaattccggtattaaaggaagagacgcag
catgcgacggtaagtgagcgcgtaacgtcgcgcttcacccgttctcattatcgccagttc
gacctcgatcaggcattttcggccaaaatctttgaccgctacctgaatctgctcgattac
agccacaacgtgctgctggcaagcgatgttgaacagttcgcgaaaaagaaaaccgagtta
ggcgatgaactgcgttcaggcaaactcgacgttttctacgatctctacaatctggcgcaa
aagcgccgttttgagcgttaccagtacgctttgtcggtactggaaaagccgatggatttc
accggcaacgacacttataaccttgaccgcagcaaagcgccctggccgaaaaacgaggct
gagttgaacgcgctgtgggacagtaaagtcaaattcgacgagttaagcctgaagctgaca
ggaaaaacggataaagaaattcgtgaaaccctgactcgccgctacaaatttgccattcgt
cgtctggcgcaaaccaacagcgaagatgttttctcgctggcaatgacggcgtttgcgcgt
gaaatcgacccgcataccaactatctttccccgcgtaataccgaacagttcaacactgaa
atgagtttgtcgctggaaggtattggcgcagtgctgcaaatggatgatgactacaccgtt
atcaattcgatggtggcaggtggtccggcagcgaagagtaaagctatcagcgttggtgac
aaaattgtcggtgttggtcaaacaggcaagccgatggttgacgtgattggctggcgtctt
gatgatgtggttgccttaattaaagggccgaagggcagtaaagttcgtctggaaatttta
cctgctggtaaagggaccaagacccgtactgtaacgttgacccgtgaacgtattcgtctc
gaagaccgcgcggttaaaatgtcggtgaagaccgtcggtaaagagaaagtcggcgtgctg
gatattccgggcttctatgtgggtttgacagacgatgtcaaagtgcaactgcagaaactg
gaaaaacagaatgtcagcagcgtcatcatcgacctgcgtagcaatggcggtggggcgtta
actgaagccgtatcgctctccggtctgtttattcctgcgggtcccattgttcaggtccgc
gataacaacggcaaggttcgtgaagatagcgataccgacggacaggttttctataaaggc
ccgctggtggtgctggttgaccgcttcagtgcttcggcttcagaaatctttgccgcggca
atgcaggattacggtcgtgcgctggttgtgggtgaaccgacgtttggtaaaggcaccgtt
cagcaataccgttcattgaaccgtatttacgatcagatgttacgtcctgaatggccagcg
ctgggttctgtgcagtacacgatccagaaattctatcgcgttaacggcggcagtacgcaa
cgtaaaggcgtaacgccagacatcatcatgccgacgggtaatgaagaaacggaaacgggt
gagaaattcgaagataacgcgctgccgtgggatagcattgatgccgcgacttatgtgaaa
tcaggagatttaacggcctttgaaccggagctgctgaaggaacataatgcgcgtatcgcg
aaagatcctgagttccagaacatcatgaaggatatcgcgcgcttcaacgctatgaaggac
aagcgcaatatcgtttctctgaattacgctgtgcgtgagaaagagaataatgaagatgat
gcgacgcgtctggcgcgtttgaacgaacgctttaaacgcgaaggtaaaccggagttgaag
aaactggatgatctaccgaaagattaccaggagccggatccttatctggatgagacggtg
aatatcgcactcgatctggcgaagcttgaaaaagccagacccgcggaacaacccgctccc
gtcaagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:682
Protein Molecular Weight:76662
Protein Theoretical pI:Not Available
Signaling Regions:
  • 1-22
Transmembrane Regions:Not Available
Protein Sequence:
>Tail-specific protease
MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQF
DLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQ
KRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLT
GKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRL
DDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVL
DIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVR
DNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETG
EKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKD
KRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETV
NIALDLAKLEKARPAEQPAPVK
References
External Links:
ResourceLink
Uniprot ID:P23865
Uniprot Name:PRC_ECOLI
CCDB:PRC_ECOLI
General Reference:Not Available