| Identification |
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| Name: | A/G-specific adenine glycosylase |
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| Synonyms: | Not Available |
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| Gene Name: | mutY |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | base-excision repair |
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| Specific Function: | Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP). |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| 4 iron, 4 sulfur cluster binding | | base-excision repair | | DNA binding | | DNA N-glycosylase activity | | hydrolase activity | | metal ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1053
atgcaagcgtcgcaattttcagcccaggttctggactggtacgataaatacgggcgaaaa
actctgccctggcaaattgacaagacgccctacaaagtatggctctcagaagtgatgttg
caacaaactcaggttgcgaccgttatcccctattttgaacgctttatggcgcgcttcccg
acggtgaccgatctcgccaatgcgccgctcgacgaagttctccacttgtggaccgggctt
ggctattacgcccgcgcgcgcaatctgcataaagcggcacaacaagtggcgaccttacac
ggcggtaaattcccggaaacctttgaggaagttgcagcactgccgggcgtcgggcgttcc
accgcaggcgcgattctctcgctttctctgggtaagcactttccgattctcgacggtaac
gtcaaacgcgtgctggcgcgctgctatgctgtaagcggctggcctgggaaaaaagaggtc
gagaataaattatggagtttgagcgagcaggtgacgcccgcggttggcgtggaacggttt
aatcaggcgatgatggatttgggtgcgatgatttgtacgcgctcgaaaccgaaatgttcg
ctctgtccgctacaaaacggatgtattgccgccgccaacaatagctgggcgctttatccg
ggcaaaaaaccgaaacagacgctgccggagcgcaccggctactttttgctattacagcac
gaagatgaagtattgctggcgcagcgtccgccgagcggattgtggggcggtttatactgt
ttcccgcagtttgccgacgaagaaagtttgcggcagtggctggcgcaacggcagattgct
gccgataacctgacgcaactgaccgcgtttcggcataccttcagccatttccacttagat
attgtgcctatgtggcttcccgtgtcgtcattcaccggctgcatggatgaaggcaatgcg
ctctggtataacttagcgcaaccgccgtcagttggcctagcggctcccgtggagcgtttg
ttacagcagttacgcactggcgcgccggtttag |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 350 |
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| Protein Molecular Weight: | 39148 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1KG2 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >A/G-specific adenine glycosylase
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFP
TVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRS
TAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERF
NQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPKQTLPERTGYFLLLQH
EDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQRQIAADNLTQLTAFRHTFSHFHLD
IVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLAAPVERLLQQLRTGAPV |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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