Identification
Name:Exodeoxyribonuclease 8
Synonyms:Not Available
Gene Name:recE
Enzyme Class:
Biological Properties
General Function:nucleic acid phosphodiester bond hydrolysis
Specific Function:Is involved in the RecE pathway of recombination. Has a strong preference for linear duplex substrate DNA and appears to be unable to initiate degradation from single-stranded breaks in DNA.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
DNA metabolic process
double-stranded DNA 5'-3' exodeoxyribonuclease activity
nucleic acid phosphodiester bond hydrolysis
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>2601
atgagcacaaaaccactcttcctgttacggaaagcgaaaaaatcatccggtgaacctgac
gtcgtcctgtgggcaagcaacgattttgaatcgacctgtgccactctggactacctgatc
gttaagtcaggtaaaaaactgagcagctattttaaagctgttgccacgaattttcctgtc
gttaatgacctgcccgctgaaggtgagatcgattttacctggagtgaacgctatcaactc
agcaaagactccatgacatgggaactaaaaccgggagcagcaccagacaacgctcactat
caaggcaataccaacgtcaacggcgaagacatgactgagattgaggagaatatgctactc
ccaatttctggccaggaactgcccattcgttggcttgctcaacacggcagcgaaaaaccg
gtaacgcacgtttcacgcgacggactccaggcattacacattgctcgggctgaagaacta
ccggctgttactgccctggctgtttcccacaaaaccagcctgctcgacccgctggaaatt
cgcgaactccacaaactggttcgtgacactgacaaagttttccctaatcctggtaattca
aacctgggactgataactgcttttttcgaagcatacctgaacgctgactacaccgatcga
ggactgctgacaaaagagtggatgaagggtaatcgtgtttcacacatcactcgcacggct
tccggtgctaatgctggcggcggaaacctcaccgatcgcggcgaaggtttcgtacacgat
ctgacgtcactggcgcgcgacgtagccactggcgtactggcccgttcaatggatctggac
atctataaccttcatccggcacacgctaaacgcattgaggaaattatcgctgaaaataaa
ccgcccttttctgttttccgcgacaaattcatcaccatgcctggcgggctggattattcc
cgcgccatcgtggttgcgtccgtaaaagaagcaccaattgggatcgaggtcatccccgcg
cacgtcactgaatatctgaacaaagtactgactgaaaccgatcatgccaaccctgatccg
gaaatcgtggatattgcctgcggtcgctcctctgccccgatgccgcagcgagtaacagaa
gaaggaaaacaggatgatgaagaaaaaccgcaaccatctggaacaacggcagttgaacag
ggagaggctgaaacaatggaaccggacgcaactgaacatcatcaggacacgcagccgctg
gatgctcagtcacaggtaaattctgttgatgcgaaatatcaggaactgcgggcagaactc
catgaagcccggaaaaacattccatcaaaaaatcctgtcgatgacgataaattgcttgct
gcatcacgtggtgaatttgttgacggaattagcgacccgaacgatccgaaatgggtaaag
gggatccagactcgcgattgtgtgtaccagaaccagccagaaacggaaaaaaccagccca
gatatgaatcaacctgagccagtagtgcaacaggaaccggaaatagcctgcaatgcctgc
ggccagactggcggggataactgccctgactgtggtgcggtgatgggcgacgcaacatac
caggaaacattcgatgaagagagtcaggttgaagctaaggaaaatgatccggaggaaatg
gaaggcgctgaacatccgcacaatgagaatgctggcagcgatccgcatcgcgattgcagt
gatgaaactggcgaagtcgcagatcccgtaatcgtagaagacatagagccaggtatttat
tacggaatttcgaatgagaattaccacgcgggtcccggtatcagtaagtctcagctcgat
gacattgctgatactccggcactatatttgtggcgtaaaaatgcccccgtggacaccaca
aagacaaaaacgctcgatttaggaactgctttccactgccgggtacttgaaccggaagaa
ttcagtaaccgctttatcgtagcacctgaatttaaccgccgtacaaacgccggaaaagaa
gaagagaaagcgtttctgatggaatgcgcaagcacaggaaaaacggttatcactgcggaa
gaaggccggaaaattgaactcatgtatcaaagcgttatggctttgccgctggggcaatgg
cttgttgaaagcgccggacacgctgaatcatcaatttactgggaagatcctgaaacagga
attttgtgtcggtgccgtccggacaaaattatccctgaatttcactggatcatggacgtg
aaaactacggcggatattcaacgattcaaaaccgcttattacgactaccgctatcacgtt
caggatgcattctacagtgacggttatgaagcacagtttggagtgcagccaactttcgtt
tttctggttgccagcacaactattgaatgcggacgttatccggttgaaattttcatgatg
ggcgaagaagcaaaactggcaggtcaacaggaatatcaccgcaatctgcgaaccctgtct
gactgcctgaataccgatgaatggccagctattaagacattatcactgccccgctgggct
aaggaatatgcaaatgactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:866
Protein Molecular Weight:96367
Protein Theoretical pI:Not Available
PDB File:3H4R
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Exodeoxyribonuclease 8
MSTKPLFLLRKAKKSSGEPDVVLWASNDFESTCATLDYLIVKSGKKLSSYFKAVATNFPV
VNDLPAEGEIDFTWSERYQLSKDSMTWELKPGAAPDNAHYQGNTNVNGEDMTEIEENMLL
PISGQELPIRWLAQHGSEKPVTHVSRDGLQALHIARAEELPAVTALAVSHKTSLLDPLEI
RELHKLVRDTDKVFPNPGNSNLGLITAFFEAYLNADYTDRGLLTKEWMKGNRVSHITRTA
SGANAGGGNLTDRGEGFVHDLTSLARDVATGVLARSMDLDIYNLHPAHAKRIEEIIAENK
PPFSVFRDKFITMPGGLDYSRAIVVASVKEAPIGIEVIPAHVTEYLNKVLTETDHANPDP
EIVDIACGRSSAPMPQRVTEEGKQDDEEKPQPSGTTAVEQGEAETMEPDATEHHQDTQPL
DAQSQVNSVDAKYQELRAELHEARKNIPSKNPVDDDKLLAASRGEFVDGISDPNDPKWVK
GIQTRDCVYQNQPETEKTSPDMNQPEPVVQQEPEIACNACGQTGGDNCPDCGAVMGDATY
QETFDEESQVEAKENDPEEMEGAEHPHNENAGSDPHRDCSDETGEVADPVIVEDIEPGIY
YGISNENYHAGPGISKSQLDDIADTPALYLWRKNAPVDTTKTKTLDLGTAFHCRVLEPEE
FSNRFIVAPEFNRRTNAGKEEEKAFLMECASTGKTVITAEEGRKIELMYQSVMALPLGQW
LVESAGHAESSIYWEDPETGILCRCRPDKIIPEFHWIMDVKTTADIQRFKTAYYDYRYHV
QDAFYSDGYEAQFGVQPTFVFLVASTTIECGRYPVEIFMMGEEAKLAGQQEYHRNLRTLS
DCLNTDEWPAIKTLSLPRWAKEYAND
References
External Links:
ResourceLink
Uniprot ID:P15032
Uniprot Name:RECE_ECOLI
PDB ID:3H4R
CCDB:RECE_ECOLI
General Reference:Not Available