Identification
Name:RNA polymerase sigma factor RpoS
Synonyms:Not Available
Gene Name:rpoS
Enzyme Class:Not Available
Biological Properties
General Function:transcription initiation from bacterial-type RNA polymerase promoter
Specific Function:Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management.Protects stationary phase cells from killing induced by endoribonuclease MazF.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
bacterial-type RNA polymerase core enzyme binding
cytoplasm
DNA binding
response to stress
sequence-specific DNA binding transcription factor activity
sigma factor activity
transcription initiation from bacterial-type RNA polymerase promoter
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>993
atgagtcagaatacgctgaaagttcatgatttaaatgaagatgcggaatttgatgagaac
ggagttgaggtttttgacgaaaaggccttagtagaacaggaacccagtgataacgatttg
gccgaagaggaactgttatcgcagggagccacacagcgtgtgttggacgcgactcagctt
taccttggtgagattggttattcaccactgttaacggccgaagaagaagtttattttgcg
cgtcgcgcactgcgtggagatgtcgcctctcgccgccggatgatcgagagtaacttgcgt
ctggtggtaaaaattgcccgccgttatggcaatcgtggtctggcgttgctggaccttatc
gaagagggcaacctggggctgatccgcgcggtagagaagtttgacccggaacgtggtttc
cgcttctcaacatacgcaacctggtggattcgccagacgattgaacgggcgattatgaac
caaacccgtactattcgtttgccgattcacatcgtaaaggagctgaacgtttacctgcga
accgcacgtgagttgtcccataagctggaccatgaaccaagtgcggaagagatcgcagag
caactggataagccagttgatgacgtcagccgtatgcttcgtcttaacgagcgcattacc
tcggtagacaccccgctgggtggtgattccgaaaaagcgttgctggacatcctggccgat
gaaaaagagaacggtccggaagataccacgcaagatgacgatatgaagcagagcatcgtc
aaatggctgttcgagctgaacgccaaacagcgtgaagtgctggcacgtcgattcggtttg
ctggggtacgaagcggcaacactggaagatgtaggtcgtgaaattggcctcacccgtgaa
cgtgttcgccagattcaggttgaaggcctgcgccgtttgcgcgaaatcctgcaaacgcag
gggctgaatatcgaagcgctgttccgcgagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:330
Protein Molecular Weight:37971
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>RNA polymerase sigma factor RpoS
MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEQEPSDNDLAEEELLSQGATQRVLDATQL
YLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNRGLALLDLI
EEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLR
TARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGDSEKALLDILAD
EKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRE
RVRQIQVEGLRRLREILQTQGLNIEALFRE
References
External Links:
ResourceLink
Uniprot ID:P13445
Uniprot Name:RPOS_ECOLI
CCDB:RPOS_ECOLI
General Reference:Not Available