Identification
Name:Uracil-DNA glycosylase
Synonyms:Not Available
Gene Name:ung
Enzyme Class:
Biological Properties
General Function:base-excision repair
Specific Function:Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
base-excision repair
cytoplasm
uracil DNA N-glycosylase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>690
atggctaacgaattaacctggcatgacgtgctggctgaagagaagcagcaaccctatttt
cttaatacccttcagaccgtcgccagcgagcggcagtccggcgtcactatctacccacca
caaaaagatgtctttaacgcgttccgctttacagagttgggtgacgttaaagtggtgatt
ctcggccaggatccttatcacggaccgggacaggcgcatggtctggcattttccgttcgt
cccggcattgccattcctccgtcattattgaatatgtataaagagctggaaaatactatt
ccgggcttcacccgccctaatcatggttatcttgaaagctgggcgcgtcagggcgttctg
ctactcaatactgtgttgacggtacgcgcaggtcaggcgcattcccacgccagcctcggc
tgggaaaccttcaccgataaagtgatcagcctgattaaccagcatcgcgaaggcgtggtg
tttttgttgtggggatcgcatgcgcaaaagaaaggggcgattatagataagcaacgccat
catgtactgaaagcaccgcatccgtcgccgctttcggcgcatcgtggattctttggctgc
aaccattttgtgctggcaaatcagtggctggaacaacgtggcgagacgccgattgactgg
atgccagtattaccggcagagagtgagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:229
Protein Molecular Weight:25693
Protein Theoretical pI:Not Available
PDB File:1EUG
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Uracil-DNA glycosylase
MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVI
LGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVL
LLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRH
HVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
References
External Links:
ResourceLink
Uniprot ID:P12295
Uniprot Name:UNG_ECOLI
PDB ID:1EUG
CCDB:UNG_ECOLI
General Reference:Not Available