Identification
Name:Ribonuclease HII
Synonyms:Not Available
Gene Name:rnhB
Enzyme Class:
Biological Properties
General Function:RNA phosphodiester bond hydrolysis, endonucleolytic
Specific Function:Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA replication, removal of RNA primer
manganese ion binding
mismatch repair
ribonuclease H2 complex
RNA binding
RNA phosphodiester bond hydrolysis, endonucleolytic
RNA-DNA hybrid ribonuclease activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>597
atgatcgaatttgtttatccgcacacgcagctggttgcgggtgtggatgaagtcggacgc
gggccgttagttggcgcggtcgtcaccgctgcggtgatccttgacccggcgcgcccgatt
gccgggctgaatgattccaaaaagctgagcgaaaaacgccgtctggcgctctatgaagag
atcaaagagaaagcgttgagctggagtctgggccgcgcggaaccccacgaaatcgacgag
ctgaacattcttcatgcgaccatgctggcgatgcagcgtgccgtcgctgggctgcatatt
gcgccggaatatgtgttgattgatggtaaccgctgcccgaaattaccgatgcctgcgatg
gctgtggtgaaaggcgatagccgcgtaccggaaatcagtgccgcgtctatcctggcgaaa
gtgacgcgtgacgccgaaatggcggcgctggatattgttttcccgcaatatggttttgcc
caacacaaagggtacccaaccgcttttcatctggaaaaactggctgaacacggcgcgacc
gaacaccatcggcgcagctttgggcctgtcaaacgcgcactgggacttgcgtcctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:198
Protein Molecular Weight:21525
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Ribonuclease HII
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEE
IKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAM
AVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGAT
EHHRRSFGPVKRALGLAS
References
External Links:
ResourceLink
Uniprot ID:P10442
Uniprot Name:RNH2_ECOLI
CCDB:RNH2_ECOLI
General Reference:Not Available