| Identification |
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| Name: | Protein translocase subunit SecA |
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| Synonyms: | Not Available |
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| Gene Name: | secA |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | protein transport by the Sec complex |
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| Specific Function: | Required for protein export, interacts with the SecYEG preprotein conducting channel. SecA has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP binding | | cell envelope Sec protein transport complex | | chaperone-mediated protein folding | | cytoplasm | | cytosol | | identical protein binding | | integral component of plasma membrane | | intracellular protein transmembrane transport | | metal ion binding | | plasma membrane | | protein import | | protein targeting | | protein transport | | protein transport by the Sec complex | | protein-transmembrane transporting ATPase activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >2706
atgctaatcaaattgttaactaaagttttcggtagtcgtaacgatcgcaccctgcgccgg
atgcgcaaagtggtcaacatcatcaatgccatggaaccggagatggaaaaactctccgac
gaagaactgaaagggaaaaccgcagagtttcgtgcacgtctggaaaaaggcgaagtgctg
gaaaatctgatcccggaagctttcgccgtggtacgtgaggcaagtaagcgcgtctttggt
atgcgtcacttcgacgttcagttactcggcggtatggttcttaacgaacgctgcatcgcc
gaaatgcgtaccggtgaaggaaaaaccctgaccgcaacgctgcctgcttacctgaacgca
ctaaccggtaaaggcgtgcacgtagttaccgtcaacgactacctggcgcaacgtgacgcc
gaaaacaaccgtccgctgtttgaattccttggcctgactgtcggtatcaacctgccgggc
atgccagcaccggcaaagcgcgaagcttacgcagctgacatcacttacggtacgaacaac
gaatacggctttgactacctgcgcgacaacatggcgttcagccctgaagaacgtgtacag
cgtaaactgcactatgcgctggtggacgaagtggactccatcctgatcgatgaagcgcgt
acaccgctgatcatttccggcccggcagaagacagctcggaaatgtataaacgcgtgaat
aaaattattccgcacctgatccgtcaggaaaaagaagactccgaaaccttccagggcgaa
ggccacttctcggtggacgaaaaatctcgccaggtgaacctgaccgaacgtggtctggtg
ctgattgaagaactgctggtgaaagagggcatcatggatgaaggggagtctctgtactct
ccggccaacatcatgctgatgcaccacgtaacggcggcgctgcgcgctcatgcgctgttt
acccgtgacgtcgactacatcgttaaagatggtgaagttatcatcgttgacgaacacacc
ggtcgtaccatgcagggccgtcgctggtccgatggtctgcaccaggctgtggaagcgaaa
gaaggtgtgcagatccagaacgaaaaccaaacgctggcttcgatcaccttccagaactac
ttccgtctgtatgaaaaactggcggggatgaccggtactgctgataccgaagctttcgaa
tttagctcaatctacaagctggataccgtcgttgttccgaccaaccgtccaatgattcgt
aaagatctgccggacctggtctacatgactgaagcggaaaaaattcaggcgatcattgaa
gatatcaaagaacgtactgcgaaaggccagccggtgctggtgggtactatctccatcgaa
aaatcggagctggtgtcaaacgaactgaccaaagccggtattaagcacaacgtcctgaac
gccaaattccacgccaacgaagcggcgattgttgctcaggcaggttatccggctgcggtg
actatcgcgaccaatatggcgggtcgtggtacagatattgtgctcggtggtagctggcag
gcagaagttgccgcgctggaaaatccgaccgcagagcaaattgaaaaaattaaagccgac
tggcaggtacgtcacgatgcggtactggaagcaggtggcctgcatatcatcggtaccgag
cgtcacgaatcccgtcgtatcgataaccagttgcgcggtcgttctggtcgtcagggggat
gctggttcttcccgtttctacctgtcgatggaagatgcgctgatgcgtatttttgcttcc
gaccgagtatccggcatgatgcgtaaactgggtatgaagccaggcgaagccattgaacac
ccgtgggtgactaaagcgattgccaacgcccagcgtaaagttgaaagccgtaacttcgac
attcgtaagcaactgctggaatatgatgacgtggctaacgatcagcgtcgcgccatttac
tcccagcgtaacgaactgttggatgtcagcgatgtgagcgaaaccattaacagcattcgt
gaagatgtgttcaaagcgaccattgatgcctacattccaccacagtcgctggaagaaatg
tgggatattccggggctgcaggaacgtctgaagaacgatttcgacctcgatttgccaatt
gccgagtggctggataaagaaccagaactgcatgaagagacgctgcgtgagcgcattctg
gcgcagtccatcgaagtgtatcagcgtaaagaagaagtggttggtgctgagatgatgcgt
cacttcgagaaaggcgtcatgctgcaaacgcttgactccctgtggaaagagcacctggca
gcgatggactatctgcgtcagggtatccacctgcgtggctacgcacagaaagatccgaag
caggaatacaaacgtgaatcgttctccatgtttgcagcgatgctggagtcgttgaaatat
gaagttatcagtacgctgagcaaagttcaggtacgtatgcctgaagaggttgaggagctg
gaacaacagcgtcgtatggaagccgagcgtttagcgcaaatgcagcagcttagccatcag
gatgacgactctgcagccgcagctgcactggcggcgcaaaccggagagcgcaaagtagga
cgtaacgatccttgcccgtgcggttctggtaaaaaatacaagcagtgccatggccgcctg
caataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 901 |
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| Protein Molecular Weight: | 102022 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1TM6 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Protein translocase subunit SecA
MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL
ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA
LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN
EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN
KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS
PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK
EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR
KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN
AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD
WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS
DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY
SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI
AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA
AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL
EQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRL
Q |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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