Identification
Name:Transcriptional regulatory protein RcsB
Synonyms:Not Available
Gene Name:rcsB
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. The system regulates expression of numerous genes, including genes involved in colanic acid capsule synthesis, biofilm formation, cell division and outer membrane proteins synthesis. Also involved, with GadE, in control of glutamate-dependent acid resistance, and, with BglJ, in derepression of the cryptic bgl operon. The RcsB-BglJ activity is probably independent of RcsB phosphorylation.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
DNA binding
intracellular
phosphorelay signal transduction system
positive regulation of cell projection organization
response to antibiotic
sequence-specific DNA binding transcription factor activity
signal transducer activity
single-species biofilm formation on inanimate substrate
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>651
atgaacaatatgaacgtaattattgccgatgaccatccgatagtcttgttcggtattcgc
aaatcacttgagcaaattgagtgggtgaatgttgtcggcgaatttgaagactctacagca
ctgatcaacaacctgccgaaactggatgcgcatgtgttgattaccgatctctccatgcct
ggcgataagtacggcgatggcattaccttaatcaagtacatcaagcgccatttcccaagc
ctgtcgatcattgttctgactatgaacaacaacccggcgattcttagtgcggtattggat
ctggatatcgaagggatcgtgctgaaacaaggtgcaccgaccgatctgccgaaagctctc
gccgcgctgcagaaagggaagaaatttaccccggaaagcgtttctcgcctgttggaaaaa
atcagtgctggtggttacggtgacaagcgtctctcgccaaaagagagtgaagttctgcgc
ctgtttgcggaaggcttcctggtgaccgagatcgctaaaaagctgaaccgcagtattaaa
accatcagtagccagaagaaatctgcgatgatgaagctgggtgtcgagaacgatatcgcc
ctgctgaattatctctcttcagtgaccttaagtccggcagataaagactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:216
Protein Molecular Weight:23670
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Transcriptional regulatory protein RcsB
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
References
External Links:
ResourceLink
Uniprot ID:P0DMC7
Uniprot Name:RCSB_ECOLI
CCDB:RCSB_ECOLI
General Reference:Not Available