| Identification |
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| Name: | Transcriptional regulatory protein RcsB |
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| Synonyms: | Not Available |
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| Gene Name: | rcsB |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | transcription, DNA-templated |
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| Specific Function: | Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. The system regulates expression of numerous genes, including genes involved in colanic acid capsule synthesis, biofilm formation, cell division and outer membrane proteins synthesis. Also involved, with GadE, in control of glutamate-dependent acid resistance, and, with BglJ, in derepression of the cryptic bgl operon. The RcsB-BglJ activity is probably independent of RcsB phosphorylation. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| DNA binding | | intracellular | | phosphorelay signal transduction system | | positive regulation of cell projection organization | | response to antibiotic | | sequence-specific DNA binding transcription factor activity | | signal transducer activity | | single-species biofilm formation on inanimate substrate | | transcription, DNA-templated |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >651
atgaacaatatgaacgtaattattgccgatgaccatccgatagtcttgttcggtattcgc
aaatcacttgagcaaattgagtgggtgaatgttgtcggcgaatttgaagactctacagca
ctgatcaacaacctgccgaaactggatgcgcatgtgttgattaccgatctctccatgcct
ggcgataagtacggcgatggcattaccttaatcaagtacatcaagcgccatttcccaagc
ctgtcgatcattgttctgactatgaacaacaacccggcgattcttagtgcggtattggat
ctggatatcgaagggatcgtgctgaaacaaggtgcaccgaccgatctgccgaaagctctc
gccgcgctgcagaaagggaagaaatttaccccggaaagcgtttctcgcctgttggaaaaa
atcagtgctggtggttacggtgacaagcgtctctcgccaaaagagagtgaagttctgcgc
ctgtttgcggaaggcttcctggtgaccgagatcgctaaaaagctgaaccgcagtattaaa
accatcagtagccagaagaaatctgcgatgatgaagctgggtgtcgagaacgatatcgcc
ctgctgaattatctctcttcagtgaccttaagtccggcagataaagactaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 216 |
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| Protein Molecular Weight: | 23670 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Transcriptional regulatory protein RcsB
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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