ECMDB

Identification

Name:

50S ribosomal protein L18

Synonyms:

Not Available

Gene Name:

rplR

Enzyme Class:

Not Available

Biological Properties

General Function:

translation

Specific Function:

This is one of the proteins that mediates the attachment of the 5S rRNA subcomplex onto the large ribosomal subunit where it forms part of the central protuberance. Binds stably to 5S rRNA; increases binding abilities of L5 in a cooperative fashion; both proteins together confer 23S rRNA binding. The 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Ribosome eco03010

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cytosolic large ribosomal subunit
rRNA binding
structural constituent of ribosome
translation

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>354
atggataagaaatctgctcgtatccgtcgtgcgacccgcgcacgccgcaagctccaggag
ctgggcgcaactcgcctggtggtacatcgtaccccgcgtcacatttacgcacaggtaatt
gcaccgaacggttctgaagttctggtagctgcttctactgtagaaaaagctatcgctgaa
caactgaagtacaccggtaacaaagacgcggctgcagctgtgggtaaagctgtcgctgaa
cgcgctctggaaaaaggcatcaaagatgtatcctttgaccgttccgggttccaatatcat
ggtcgtgtccaggcactggcagatgctgcccgtgaagctggccttcagttctaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

117

Protein Molecular Weight:

12769

Protein Theoretical pI:

Not Available

PDB File:

1ML5

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>50S ribosomal protein L18
MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAE
QLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF

References

External Links:

Resource	Link
Uniprot ID:	P0C018
Uniprot Name:	RL18_ECOLI
PDB ID:	1ML5
CCDB:	RL18_ECOLI

General Reference:

Not Available

50S ribosomal protein L18 (P0C018)