Identification
Name:Protein-export membrane protein SecG
Synonyms:Not Available
Gene Name:secG
Enzyme Class:Not Available
Biological Properties
General Function:protein transport by the Sec complex
Specific Function:Subunit of the protein translocation channel SecYEG. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY. Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Transports:
    Transport References:Not Available
    Metabolites:
    ECMDB IDNameView
    GO Classification:
    Function
    integral component of membrane
    intracellular
    intracellular protein transmembrane transport
    intracellular protein transport
    P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    plasma membrane
    protein secretion
    protein transport by the Sec complex
    Gene Properties
    Blattner:Not Available
    Gene OrientationNot Available
    Centisome Percentage:Not Available
    Left Sequence EndNot Available
    Right Sequence EndNot Available
    Gene Sequence:
    >333
    atgtatgaagctcttttagtagttttccttattgtggcaattggccttgttggtctgatc
    atgctgcagcaaggtaaaggcgctgatatgggagcctccttcggagcaggcgcttccgct
    acgctgtttggttcaagtggttctggtaacttcatgacccgcatgacggcgctgctggca
    acgttattcttcatcatcagtctggtgctgggtaacatcaatagcaacaaaaccaataaa
    ggtagcgaatgggaaaatctgagtgcaccggcgaaaaccgaacaaactcagccagctgct
    ccggctaagccgaccagcgatatcccgaactaa
    Protein Properties
    Pfam Domain Function:Not Available
    Protein Residues:110
    Protein Molecular Weight:11365
    Protein Theoretical pI:Not Available
    PDB File:2AKH
    Signaling Regions:Not Available
    Transmembrane Regions:
    • 14-25
    • 51-66
    Protein Sequence:
    >Protein-export membrane protein SecG
    MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA
    TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN
    References
    External Links:
    ResourceLink
    Uniprot ID:P0AG99
    Uniprot Name:SECG_ECOLI
    PDB ID:2AKH
    CCDB:SECG_ECOLI
    General Reference:Not Available