Identification
Name:Protein-export membrane protein SecG
Synonyms:Not Available
Gene Name:secG
Enzyme Class:Not Available
Biological Properties
General Function:protein transport by the Sec complex
Specific Function:Subunit of the protein translocation channel SecYEG. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY. Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
integral component of membrane
intracellular
intracellular protein transmembrane transport
intracellular protein transport
P-P-bond-hydrolysis-driven protein transmembrane transporter activity
plasma membrane
protein secretion
protein transport by the Sec complex
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>333
atgtatgaagctcttttagtagttttccttattgtggcaattggccttgttggtctgatc
atgctgcagcaaggtaaaggcgctgatatgggagcctccttcggagcaggcgcttccgct
acgctgtttggttcaagtggttctggtaacttcatgacccgcatgacggcgctgctggca
acgttattcttcatcatcagtctggtgctgggtaacatcaatagcaacaaaaccaataaa
ggtagcgaatgggaaaatctgagtgcaccggcgaaaaccgaacaaactcagccagctgct
ccggctaagccgaccagcgatatcccgaactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:110
Protein Molecular Weight:11365
Protein Theoretical pI:Not Available
PDB File:2AKH
Signaling Regions:Not Available
Transmembrane Regions:
  • 14-25
  • 51-66
Protein Sequence:
>Protein-export membrane protein SecG
MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA
TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN
References
External Links:
ResourceLink
Uniprot ID:P0AG99
Uniprot Name:SECG_ECOLI
PDB ID:2AKH
CCDB:SECG_ECOLI
General Reference:Not Available