ECMDB

Identification

Name:

Protein-export membrane protein SecG

Synonyms:

Not Available

Gene Name:

secG

Enzyme Class:

Not Available

Biological Properties

General Function:

protein transport by the Sec complex

Specific Function:

Subunit of the protein translocation channel SecYEG. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY. Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Protein export eco03060

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
integral component of membrane
intracellular
intracellular protein transmembrane transport
intracellular protein transport
P-P-bond-hydrolysis-driven protein transmembrane transporter activity
plasma membrane
protein secretion
protein transport by the Sec complex

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>333
atgtatgaagctcttttagtagttttccttattgtggcaattggccttgttggtctgatc
atgctgcagcaaggtaaaggcgctgatatgggagcctccttcggagcaggcgcttccgct
acgctgtttggttcaagtggttctggtaacttcatgacccgcatgacggcgctgctggca
acgttattcttcatcatcagtctggtgctgggtaacatcaatagcaacaaaaccaataaa
ggtagcgaatgggaaaatctgagtgcaccggcgaaaaccgaacaaactcagccagctgct
ccggctaagccgaccagcgatatcccgaactaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

110

Protein Molecular Weight:

11365

Protein Theoretical pI:

Not Available

PDB File:

2AKH

Signaling Regions:

Not Available

Transmembrane Regions:

14-25
51-66

Protein Sequence:

>Protein-export membrane protein SecG
MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA
TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN

References

External Links:

Resource	Link
Uniprot ID:	P0AG99
Uniprot Name:	SECG_ECOLI
PDB ID:	2AKH
CCDB:	SECG_ECOLI

General Reference:

Not Available

Protein-export membrane protein SecG (P0AG99)