Protein translocase subunit SecE (P0AG96)

Identification
Name:Protein translocase subunit SecE
Synonyms:Not Available
Gene Name:secE
Enzyme Class:Not Available
Biological Properties
General Function:protein transport by the Sec complex
Specific Function:Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Transports:
    Transport References:Not Available
    Metabolites:
    ECMDB IDNameView
    GO Classification:
    Function
    cell envelope Sec protein transport complex
    integral component of membrane
    integral component of plasma membrane
    intracellular
    intracellular protein transmembrane transport
    intracellular protein transport
    P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    plasma membrane
    protein secretion
    protein targeting
    protein transport by the Sec complex
    Gene Properties
    Blattner:Not Available
    Gene OrientationNot Available
    Centisome Percentage:Not Available
    Left Sequence EndNot Available
    Right Sequence EndNot Available
    Gene Sequence:
    >384
atgagtgcgaataccgaagctcaaggaagcgggcgcggcctggaagcgatgaagtgggtc
gttgtggtggcattgctcctggtggcgattgtcggcaactatctttatcgcgacattatg
ctgccgctgcgtgcgctggccgtagtaattctgattgctgcagcgggtggtgtcgcgctg
ttaacgacaaaaggtaaagctaccgttgcttttgcccgtgaagcgcgtaccgaagtccgt
aaggtcatttggccgactcgccaggaaacattgcacaccacgctgattgtggctgcggtt
accgcagtaatgtcactgatcctgtggggactggatggtattctggttcgcctggtatcc
tttatcactggcctgaggttctga
    Protein Properties
    Pfam Domain Function:Not Available
    Protein Residues:127
    Protein Molecular Weight:13643
    Protein Theoretical pI:Not Available
    PDB File:2AKH
    Signaling Regions:Not Available
    Transmembrane Regions:
    • 20-32
    • 49-60
    • 98-115
    Protein Sequence:
    >Protein translocase subunit SecE
MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVAL
LTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVS
FITGLRF
    References
    External Links:
    ResourceLink
    Uniprot ID:P0AG96
    Uniprot Name:SECE_ECOLI
    PDB ID:2AKH
    CCDB:SECE_ECOLI
    General Reference:Not Available