Identification
Name:50S ribosomal protein L6
Synonyms:Not Available
Gene Name:rplF
Enzyme Class:Not Available
Biological Properties
General Function:translation
Specific Function:This protein binds directly to at least 2 domains of the 23S ribosomal RNA, thus is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.Gentamicin-resistant mutations in this protein affect translation fidelity.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytosolic large ribosomal subunit
response to antibiotic
rRNA binding
structural constituent of ribosome
translation
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>534
atgtctcgtgttgctaaagcaccggtcgttgttcctgccggcgttgacgtaaaaatcaac
ggtcaggttattacgatcaaaggtaaaaacggcgagctgactcgtactctcaacgatgct
gttgaagttaaacatgcagataataccctgaccttcggtccgcgtgatggttacgcagac
ggttgggcacaggctggtaccgcgcgtgccctgctgaactcaatggttatcggtgttacc
gaaggcttcactaagaagctgcagctggttggtgtaggttaccgtgcagcggttaaaggc
aatgtgattaacctgtctctgggtttctctcatcctgttgaccatcagctgcctgcgggt
atcactgctgaatgtccgactcagactgaaatcgtgctgaaaggcgctgataagcaggtg
atcggccaggttgcagcggatctgcgcgcctaccgtcgtcctgagccttataaaggcaag
ggtgttcgttacgccgacgaagtcgtgcgtaccaaagaggctaagaagaagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:177
Protein Molecular Weight:18903
Protein Theoretical pI:Not Available
PDB File:1EG0
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>50S ribosomal protein L6
MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYAD
GWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAG
ITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
References
External Links:
ResourceLink
Uniprot ID:P0AG55
Uniprot Name:RL6_ECOLI
PDB ID:1EG0
CCDB:RL6_ECOLI
General Reference:Not Available